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1-β-D-Glucosylsphingosine (d18:1) (Synonyms: Glucosyl-C18-Sphingosine, Glucosylsphingosine (d18:1), 1-β-D-Glucosylsphingosine (synthetic))

Catalog No.GC42051

1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.

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1-β-D-Glucosylsphingosine (d18:1) Chemical Structure

Cas No.: 52050-17-6

Size Price Stock Qty
1mg
$142.00
In stock
5mg
$425.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher's disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease. This product is a fully synthetic 1-β-D-glucosylsphingosine.

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