1-O-Hexadecyl-sn-glycerol (Synonyms: α-Chimyl Alcohol, (S)-(+)-Chimyl Alcohol) |
| Catalog No.GC18235 |
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 506-03-6
Sample solution is provided at 25 µL, 10mM.
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1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.
References:
[1].Yokota, M., Yahagi, S., Tokudome, Y., et al. Chimyl alcohol suppresses PGE2 synthesis by human epidermal keratinocytes through the activation of PPAR-γ J. Oleo. Sci. 67(4), 455-462 (2018).
[2].Maulik, N., Tosaki, A., Engelman, R.M., et al. Myocardial salvage by chimyl alcohol: Possible role of peroxisomal dysfunction in reperfusion injury Ann. N.Y. Acad. Sci. 723(1), 380-384 (1994).
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