Home>>10-PAHSA 13C4

10-PAHSA 13C4

Catalog No.GC41870

10-PAHSA 13C4 is an isotopically enriched form of the polyunsaturated fatty acid 10-PASHA with carbon-13 incorporated at positions 1, 2, 3, and 4.

Products are for research use only. Not for human use. We do not sell to patients.

10-PAHSA 13C4 Chemical Structure

Size Price Stock Qty
100μg
$111.00
In stock
250μg
$250.00
In stock
500μg
$445.00
In stock
1mg
$780.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

10-PAHSA 13C4 is an isotopically enriched form of the polyunsaturated fatty acid 10-PASHA with carbon-13 incorporated at positions 1, 2, 3, and 4. It is intended for use as an internal standard for the quantification of 10-PAHSA by GC- or LC-MS. 10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). It is a FAHFA in which palmitic acid is esterified to 10-hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 10-PAHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.

Chemical Properties

Cas No. SDF
Canonical SMILES CCCCCCCCC(O[13C]([13CH2][13CH2][13CH2]CCCCCCCCCCCC)=O)CCCCCCCCC(O)=O
Formula C30[13C]4H66O4 M.Wt 542.9
Solubility DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.842 mL 9.2098 mL 18.4196 mL
5 mM 0.3684 mL 1.842 mL 3.6839 mL
10 mM 0.1842 mL 0.921 mL 1.842 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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