Home>>Analytical Standards>>11-dehydro Thromboxane B2

11-dehydro Thromboxane B2 (Synonyms: 11-dehydro TXB2, 11-keto TXB2)

Catalog No.GC18660

Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.

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11-dehydro Thromboxane B2 Chemical Structure

Cas No.: 67910-12-7

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10µg
$215.00
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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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Background

Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis. The mean plasma level in human males is 0.9-4.3 pg/ml and the half life is 45-60 minutes. Urinary concentrations of 11-dehydro TXB2 are approximately 30-70 ng/mmol creatinine.

Chemical Properties

Cas No. 67910-12-7 SDF
Synonyms 11-dehydro TXB2, 11-keto TXB2
Chemical Name 9α,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic acid
Canonical SMILES CCCCC[C@H](O)/C=C/[C@H]1OC(C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O)=O
Formula C20H32O6 M.Wt 368.5
Solubility DMF: >50 mg/ml (from TXB2),DMSO: >25 mg/ml (from TXB2),Ethanol: >100 mg/ml (from TXB2),PBS pH 7.2: >100 µ g/ml (from TXB2) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.7137 mL 13.5685 mL 27.137 mL
5 mM 0.5427 mL 2.7137 mL 5.4274 mL
10 mM 0.2714 mL 1.3569 mL 2.7137 mL
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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