11-deoxy Prostaglandin E1 (Synonyms: 11deoxy PGE1) |
| Catalog No.GC18634 |
11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 37786-00-8
Sample solution is provided at 25 µL, 10mM.
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11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1. Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2. However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC50 of 0.25 uM. 11-deoxy PGE1 also exhibits vasodepressor and bronchodilator responses in guinea pigs. 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The Ki values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.
Review for 11-deoxy Prostaglandin E1
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
Review for 11-deoxy Prostaglandin E1
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