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2'-Deoxy-5'-O-DMT-2'-fluorouridine

Catalog No.GC67627

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5'-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.

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2'-Deoxy-5'-O-DMT-2'-fluorouridine Chemical Structure

Cas No.: 146954-74-7

Size Price Stock Qty
5g
$329.00
In stock
25g
$1,153.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5'-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity[1].

2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM[1].

[1]. Christopher McGuigan, et al. Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues. ChemistryOpen. 2016 Jan 21;5(3):227-35.

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