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3-Hydroxy-4-methoxycinnamic acid Catalog No.GN10169

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20mg
$75.00
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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Chemical Properties

Cas No. 537-73-5 SDF
Chemical Name (E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid
Canonical SMILES COC1=C(C=C(C=C1)C=CC(=O)O)O
Formula C10H10O4 M.Wt 194.18
Solubility DMF: 20 mg/mL,DMF:PBS(pH 7.2)(1:6): 0.14 mg/mL,DMSO: 15 mg/mL,Ethanol: 10 mg/mL Storage
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use.

References:
[1]. Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204.