4-Deoxypyridoxine (hydrochloride) (Synonyms: 4-Deoxypyridoxine, DOP, 4-DPD) |
| Catalog No.GC42369 |
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 148-51-6
Sample solution is provided at 25 µL, 10mM.
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4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. 4-DPD (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. 4-DPD reduces TNF-α and IL-6 production in mice infected with T. spiralis.
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