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5-Androstenetriol (Synonyms: Δ5-AT)

Catalog No.GC49827

An active metabolite of DHEA

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5-Androstenetriol Chemical Structure

Cas No.: 4150-30-5

Size Price Stock Qty
1 mg
$103.00
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5 mg
$465.00
In stock
10 mg
$825.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

5-Androstenetriol is a steroid and an active metabolite of dehydroepiandrosterone .1 In vivo, 5-androstenetriol (0.75 mg/25 g body weight) reduces radiation-induced lethality and induces hematopoietic recovery from surviving stem cells in mice. It increases survival in a rat model of surgical trauma-induced sepsis when administered at a dose of 40 mg/kg.2 Urinary levels of 5-androstenetriol are increased in women with androgenic alopecia.3

1.Loria, R.M., Conrad, D.H., Huff, T., et al.Androstenetriol and androstenediol. Protection against lethal radiation and restoration of immunity after radiation injuryAnn. N. Y. Acad. Sci.917(1)860-867(2000) 2.Marcu, A.C., Kielar, N.D., Paccione, K.E., et al.Androstenetriol improves survival in a rodent model of traumatic shockResuscitation71(3)379-386(2006) 3.Juricskay, S., and Telegdy, E.Urinary steroids in women with androgenic alopeciaClin. Biochem.33(2)97-101(2000)

Chemical Properties

Cas No. 4150-30-5 SDF Download SDF
Synonyms Δ5-AT
Canonical SMILES C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)([C@H]([C@@H](C4)O)O)C
Formula C19H30O3 M.Wt 306.4
Solubility DMSO: soluble,Ethanol: soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.2637 mL 16.3185 mL 32.6371 mL
5 mM 0.6527 mL 3.2637 mL 6.5274 mL
10 mM 0.3264 mL 1.6319 mL 3.2637 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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