5-fluoro SDB-005 |
| Catalog No.GC42538 |
5-fluoro SDB-005 is an analog of SDB-005, a synthetic cannabinoid (CB) that activates the central CB1 receptor (EC50 = 21 nM) preferentially over the peripheral CB2 receptor (EC50 = 140 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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5-fluoro SDB-005 is an analog of SDB-005, a synthetic cannabinoid (CB) that activates the central CB1 receptor (EC50 = 21 nM) preferentially over the peripheral CB2 receptor (EC50 = 140 nM).[1] While the properties of this compound are not known, the addition of fluorine to the terminal carbon of the alkyl chain in similar cannabimimetic compounds typically increases affinity for both CB receptors significantly.[2] This product is intended for research and forensic applications.
Reference:
[1]. Banister, S.D., Wilkinson, S.M., Longworth, M., et al. The synthesis and pharmacological evaluation of adamantane-derived indoles: Cannabimimetic drugs of abuse. ACS Chem.Neurosci. 4(7), 1081-1092 (2013).
[2]. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. PCT/US00/28832, (2001).
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