5-Fluoropentylindole |
| Catalog No.GC40502 |
A wide variety of aminoalkylindole analogs are potent synthetic cannabinoids (CBs), including many of the JWH compounds.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1859218-30-6
Sample solution is provided at 25 µL, 10mM.
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A wide variety of aminoalkylindole analogs are potent synthetic cannabinoids (CBs), including many of the JWH compounds.[1] An alkyl chain of five carbons in length produces compounds with high affinity for both the central CB1 and the peripheral CB2 receptors.[2] The addition of a terminal fluorine to the pentyl chain can further increase affinity for both CB receptors.[3] 5-Fluoropentylindole is the base structure for a variety of synthetic CBs. A range of structures are commonly added to this base via a ketone linkage at the three position of the indole. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Reference:
[1]. Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. Journal of Pharmacology and Experimental Therapeutics 285(3), 995-1004 (1998).
[2]. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).
[3]. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. PCT/US00/28832, (2001).
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