5-hydroxy-Nω-methyl Tryptamine (oxalate) (Synonyms: N-methyl-5-HT, N-methyl Serotonin, N-methyl-5-hydroxy Tryptamine) |
| Catalog No.GC42553 |
5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants.
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Cas No.: 15558-50-6
Sample solution is provided at 25 µL, 10mM.
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5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay). 5-hydroxy-Nω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-Nω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.
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