5-Hydroxyindole-3-acetic acid (Synonyms: 5-HIAA, 5-Hydroxyindoleacetic Acid, 5-hydroxy IAA, NSC 90432) |
| Catalog No.GC33698 |
A serotonin metabolite
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Cas No.: 54-16-0
Sample solution is provided at 25 µL, 10mM.
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5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
5-Hydroxyindole-3-acetic acid (5HIAA) is a metabolite issued from serotonin metabolism, and the latter is synthetized from the essential amino acid tryptophan. Serotonin is mainly metabolised by monoamine oxidase in the liver and the lungs[1].
[1]. Corcuff JB, et al. Urinary sampling for 5HIAA and metanephrines determination: revisiting the recommendations. Endocr Connect. 2017 Aug;6(6):R87-R98.
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