5(S)-HETE lactone (Synonyms: 5(S)-Hydroxyeicosatetraenoic Acid lactone) |
| Catalog No.GC40829 |
5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE.
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Cas No.: 127708-42-3
Sample solution is provided at 25 µL, 10mM.
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5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (±)5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 µM) may be entirely due to the 5(S) isomer, but the enantiomers have not been tested separately.
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