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6α-Methylprednisolone 21-hemisuccinate sodium salt (Synonyms: Methylprednisolone 21-succinate, MPS, NSC 48989, U-9088)

Catalog No.GC60535

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6α-Methylprednisolone 21-hemisuccinate sodium salt Chemical Structure

Cas No.: 2375-03-3

Size Price Stock Qty
10mM (in 1mL DMSO)
$43.00
In stock
10mg
$51.00
In stock
50mg
$149.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of 6α-Methylprednisolone 21-hemisuccinate sodium salt

6α-Methylprednisolone 21-hemisuccinate sodium salt is a glucocorticoid of slightly longer half-life than that of Prednisolone. It has potential uses in antiinflammatory agents.

Chemical Properties of 6α-Methylprednisolone 21-hemisuccinate sodium salt

Cas No. 2375-03-3 SDF
Synonyms Methylprednisolone 21-succinate, MPS, NSC 48989, U-9088
Canonical SMILES C[C@@]12[C@](C(COC(CCC(O[Na])=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
Formula C26H33NaO8 M.Wt 496.53
Solubility DMSO: ≥ 25 mg/mL (50.35 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 6α-Methylprednisolone 21-hemisuccinate sodium salt

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1 mg 5 mg 10 mg
1 mM 2.014 mL 10.0699 mL 20.1398 mL
5 mM 402.8 μL 2.014 mL 4.028 mL
10 mM 201.4 μL 1.007 mL 2.014 mL
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In vivo Formulation Calculator (Clear solution) of 6α-Methylprednisolone 21-hemisuccinate sodium salt

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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