6-Chloropurine Riboside (Synonyms: NSC 4910) |
| Catalog No.GC49551 |
A nucleoside precursor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 5399-87-1
Sample solution is provided at 25 µL, 10mM.
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6-Chloropurine riboside is a nucleoside precursor.1 It has been used in the synthesis of adenosine derivatives with antiproliferative activity in human gastric cancer cells expressing the adenosine A3 receptor. 6-Chloropurine riboside has also been used in the synthesis of N6-benzyladenosine derivatives with antiproliferative activity in a variety of cancer cells or inhibitory activity against T. gondii replication in CRL-1634/Hs27 human skin fibroblasts.2,3
1.Zurita, F.V., Vega, N.B., and Cabrera, M.G.Semisynthesis, characterization and evaluation of new adenosine derivatives as antiproliferative agentsMolecules23(5)1111(2018) 2.Dolezal, K., Popa, I., HauserovÁ, E., et al.Preparation, biological activity and endogenous occurrence of N6-benzyladenosinesBioorg. Med. Chem.15(11)3737-3747(2007) 3.Kim, Y.A., Sharon, A., Chu, C.K., et al.Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agentsBiochem. Pharmacol.73(10)1558-1572(2007)
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