6-O-desmethyl Donepezil |
| Catalog No.GC42584 |
6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 120013-56-1
Sample solution is provided at 25 µL, 10mM.
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6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 µM in HEK293 cells expressing hERG).
Review for 6-O-desmethyl Donepezil
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
Review for 6-O-desmethyl Donepezil
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