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8-bromo-Cyclic AMP (Synonyms: 8-Bromoadenosine 3',5'-cyclic monophosphate, 8-Br-cAMP, 8-bromo-cAMP, NSC 171719)

Catalog No.GC42622

8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase.

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8-bromo-Cyclic AMP Chemical Structure

Cas No.: 23583-48-4

Size Price Stock Qty
10mg
$67.00
In stock
25mg
$143.00
In stock
50mg
$235.00
In stock
100mg
$369.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase. It can activate cAMP-dependent protein kinase, inhibiting growth, decreasing proliferation, increasing differentiation, and inducing apoptosis of cancer cells.

Chemical Properties

Cas No. 23583-48-4 SDF
Synonyms 8-Bromoadenosine 3',5'-cyclic monophosphate, 8-Br-cAMP, 8-bromo-cAMP, NSC 171719
Canonical SMILES OP1(OC[C@]2([H])[C@@]([C@@H](O)[C@H](N3C(N=CN=C4N)=C4N=C3Br)O2)([H])O1)=O
Formula C10H11BrN5O6P M.Wt 408.1
Solubility PBS (pH 7.2): 3 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.4504 mL 12.2519 mL 24.5038 mL
5 mM 0.4901 mL 2.4504 mL 4.9008 mL
10 mM 0.245 mL 1.2252 mL 2.4504 mL
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Reviews

Review for 8-bromo-Cyclic AMP

Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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