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α-CEHC

Catalog No.GC11123

α-CEHC Chemical Structure

A major metabolite of δ-tocopherol

Size Price Stock Qty
1mg
$26.00
In stock
5mg
$117.00
In stock
10mg
$208.00
In stock
25mg
$455.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Background

Molecules having vitamin E antioxidant activity include four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ). α-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation. α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation. The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate. α-CEHC was only excreted when a threshold concentration of 7-9 &#181mol α-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of α-CEHC may be considered to be a marker of optimum vitamin E intake.

Chemical Properties

Cas No. 4072-32-6 SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES CC1=C(OC(CCC(O)=O)(C)CC2)C2=C(C)C(O)=C1C
Formula C16H22O4 M.Wt 278.3
Solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2)(1:1): .25 mg/ml,Ethanol: 10 mg/ml Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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