A 1070722 |
| Catalog No.GC10336 |
GSK-3 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1384424-80-9
Sample solution is provided at 25 µL, 10mM.
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A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain[1].
References:
[1]. Prabhakaran J, et al. Radiosynthesis and in Vivo Evaluation of [11C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain. ACS Chem Neurosci. 2017 Aug 16;8(8):1697-1703.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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