A 410099.1, amine |
| Catalog No.GC50466 |
A 410099.1, amine is afunctionalizedIAP ligand and can be used for the synthesis of PROTACs, such as PROTACs targeting BTK (PROTACs 4 and 5).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2374122-37-7
Sample solution is provided at 25 µL, 10mM.
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Functionalized IAP ligand for PROTAC® research and development. Boc protected A 410099.1 (Cat.No. 6470). Supplied with an amine functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Tinworth et al (2019) PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding. ACS Chem.Biol. 14 342 PMID:30807093
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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