α-hydroxy Alprazolam (Synonyms: U-40125) |
| Catalog No.GC18276 |
α-hydroxy Alprazolam is a certified reference material categorized as a benzodiazepine.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 37115-43-8
Sample solution is provided at 25 µL, 10mM.
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α-hydroxy Alprazolam is a certified reference material categorized as a benzodiazepine. It is a major active metabolite of alprazolam that has a higher urinary recovery than 4-hydroxy alprazolam , another major metabolite. It is also a metabolite of adinazolam . This product is intended for research and forensic applications.
References:
[1]. Greenblatt, D.J., and Wright, C.E. Clinical pharmacokinetics of alprazolam. Therapeutic implications Clin. Pharmacokinet. 24(6), 453-471 (1993).
[2]. Shin, M., Ki, D., Kang, S., et al. Screening of multiple drugs of abuse and metabolites in urine using LC/MS/MS with polarity switching electrospray ionization Arch. Pharm. Res. 37(6), 760-772 (2014).
[3]. Allqvist, A., Wennerholm, A., Svensson, J.-O., et al. Simultaneous quantification of alprazolam, 4- and α-hydroxyalprazolam in plasma samples using liquid chromatography mass spectrometry J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 814(1), 127-131 (2005).
[4]. Fraser, A.D., Isner, A.F., and Bryan, W. Urinary screening for adinazolam and its major metabolites by the Emit d.a.u. and FPIA benzodiazepine assays with confirmation by HPLC J. Anal. Toxicol. 17(7), 427-431 (1993).
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