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Altertoxin I (Synonyms: Dihydroalterperylenol)

Catalog No.GC42772

Altertoxin I is a natural mycotoxin first isolated from fungi of the genus Alternaria.

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Altertoxin I Chemical Structure

Cas No.: 56258-32-3

Size Price Stock Qty
500ug
$447.00
In stock
1mg
$848.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Product Documents

Quality Control & SDS

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Background

Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi, which is mutagenic and cytotoxic, and can weakly disrupts metabolic communication[1].

References:
[1]. Jarolim K, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017 Jan;91(1):203-216.
[2]. Boutin BK, et al. Effects of purified altertoxins I, II, and III in the metabolic communication V79 system. J Toxicol Environ Health. 1989;26(1):75-81.
[3]. Stack ME, et al. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl Environ Microbiol. 1986 Oct;52(4):718-22.

Chemical Properties

Cas No. 56258-32-3 SDF
Synonyms Dihydroalterperylenol
Chemical Name (1S,12aR,12bS)-1,2,11,12,12a,12b-hexahydro-1,4,9,12a-tetrahydroxy-3,10-perylenedione
Canonical SMILES O=C(CC[C@@]1(O)[C@@]([C@@H](O)C2)([H])C3=C4C=CC(O)=C3C2=O)C5=C1C4=CC=C5O
Formula C20H16O6 M.Wt 352.3
Solubility 10mg/mL in dichloromethane Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.8385 mL 14.1924 mL 28.3849 mL
5 mM 0.5677 mL 2.8385 mL 5.677 mL
10 mM 0.2838 mL 1.4192 mL 2.8385 mL
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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