Amylin (8-37) (human) (trifluoroacetate salt) (Synonyms: IAPP (8-37) (human), Islet Amyloid Polypeptide (8-37) (human)) |
| Catalog No.GC42794 |
Amylin (8-37) is a peptide fragment of amylin.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Amylin (8-37) is a peptide fragment of amylin . It inhibits osteoblast proliferation, but not bone resorption, induced by full-length human amylin and does not act as an agonist at amylin receptors. Amylin (8-37) induces formation of polymorphic fibrils containing coiled and laterally-associated sheet structures. It is cytotoxic to RINm5F islet β-cells in vitro when used at a concentration of 25 µM, an effect that is inversely correlated with mature fibril content.
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