Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt) (Synonyms: Cyclized APP (96-110), Cyclized APP96-110) |
| Catalog No.GC40126 |
Amyloid-β precursor protein (96-110) peptide (cyclized) is a synthetic peptide consisting of amino acids 96-110 of amyloid precursor peptide (APP) that is cyclized via a bridge between the cysteine residues at positions 3 and 10.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Amyloid-β precursor protein (96-110) peptide (cyclized) is a synthetic peptide consisting of amino acids 96-110 of amyloid precursor peptide (APP) that is cyclized via a bridge between the cysteine residues at positions 3 and 10. It is homologous to the heparin-binding domain of human APP and inhibits binding of [125I]APP to heparin in vitro with an IC50 value of approximately 100 nM. Amyloid-β precursor protein (96-110) peptide (cyclized) inhibits neurite outgrowth induced by APP and mouse postnatal heparan sulfate proteoglycans (HSPG) in primary mouse hippocampal neurons when used at a concentration of 10 μg/ml.
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