Anabasine ((S)-Anabasine) |
| Catalog No.GC30866 |
Anabasine ((S)-Anabasine) ((S)-Anabasine ((S)-Anabasine)) is an alkaloid that found as a minor component in tobacco (Nicotiana).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 494-52-0
Sample solution is provided at 25 µL, 10mM.
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Anabasine is a nicotinic receptor agonist.
Anabasine significantly reverses the impairment at the 0.2 mg/kg (p<0.05) and 2 mg/kg doses (p<0.025). Anabasine does not have any significant effects on response latency when administered alone. The 0.06 mg/kg Anabasine dose, in fact, significantly (p<0.05) exacerbates the dizocilpine-induced impairment. None of these Anabasine doses affects choice accuracy on their own. Individual dose comparisons show that the 0.06 mg/kg Anabasine dose plus dizocilpine (6.7±2.6) causes a significant (p<0.05) increase in non-response trials compare with dizocilpine alone (2.1±0.8)[1].
[1]. Levin ED, et al. Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats. J Psychopharmacol. 2014 Oct;28(10):915-22.
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