Antileukinate |
| Catalog No.GC42817 |
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 138559-60-1
Sample solution is provided at 25 µL, 10mM.
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Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 µM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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