Antitrypanosomal agent 1 |
| Catalog No.GC39478 |
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 75144-12-6
Sample solution is provided at 25 µL, 10mM.
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Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity[1].
[1]. Martyn DC, et al. High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1280-3.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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