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AR-13324 mesylate Catalog No.GC19034

Size Price Stock Qty
2mg
$118.30
In stock
5mg
$236.60
In stock
10mg
$422.50
In stock
50mg
$1,605.50
In stock
100mg
$2,450.50
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 1422144-42-0 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES CC1=CC(C)=C(C(OCC2=CC=C([C@@H](CN)C(NC3=CC(C=CN=C4)=C4C=C3)=O)C=C2)=O)C=C1.CS(=O)(O)=O.CS(=O)(O)=O
Formula C30H35N3O9S2 M.Wt 645.74
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.

References:
[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.
[2]. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.