الصفحة الرئيسية>>Lipids>> Lipid-Based Drug Delivery>>1,2-Didecanoyl PC

1,2-Didecanoyl PC (Synonyms: 1,2Didecanoyl Phosphatidylcholine, Didecanoyl Lecithin, 1,2-DPC)

رقم الكتالوجGC41788

Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane.

Products are for research use only. Not for human use. We do not sell to patients.

1,2-Didecanoyl PC التركيب الكيميائي

Cas No.: 3436-44-0

الحجم السعر المخزون الكميّة
5mg
19٫00
متوفر
10mg
35٫00
متوفر
25mg
84٫00
متوفر
50mg
146٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of 1,2-Didecanoyl PC

Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of intranasally applied human growth hormone is enhanced when coadministered with the absorption enhancer 1,2-didecanoyl PC.

Chemical Properties of 1,2-Didecanoyl PC

Cas No. 3436-44-0 SDF
المرادفات 1,2Didecanoyl Phosphatidylcholine, Didecanoyl Lecithin, 1,2-DPC
Canonical SMILES CCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCCCCCCC
Formula C28H56NO8P M.Wt 565.7
الذوبان Ethanol: 30 mg/ml,DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:1): 0.5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 1,2-Didecanoyl PC

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.7677 mL 8.8386 mL 17.6772 mL
5 mM 0.3535 mL 1.7677 mL 3.5354 mL
10 mM 0.1768 mL 0.8839 mL 1.7677 mL
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In vivo Formulation Calculator (Clear solution) of 1,2-Didecanoyl PC

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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