الصفحة الرئيسية>>Infectious Disease>> Bacterial Diseases>>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

رقم الكتالوجGC46385

A ManNAc analog and building block

Products are for research use only. Not for human use. We do not sell to patients.

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose التركيب الكيميائي

Cas No.: 68733-20-0

الحجم السعر المخزون الكميّة
10 mg
94٫00
متوفر
50 mg
237٫00
متوفر
100 mg
377٫00
متوفر
250 mg
824٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


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Sample solution is provided at 25 µL, 10mM.

Description of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block.1,2 It has been used as a precursor in the synthesis of differently substituted trimers of the group A N. meningitidis capsular polysaccharide repeating unit for use in immunological experiments.2 It has also been used in the synthesis of fluorescent probes for lysosomal labeling.3

1.Saxon, E., Luchansky, S.J., Hang, H.C., et al.Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligationJ. Am. Chem. Soc.124(50)14893-14902(2002) 2.SlÄttegÅrd, R., Teodorovic, P., Kinfe, H.H., et al.Synthesis of structures corresponding to the capsular polysaccharide of Neisseria meningitidis group AOrg. Biomol. Chem.3(20)3782-3787(2005) 3.Yapici, N.B., Bi, Y., Li, P., et al.Highly stable and sensitive fluorescent probes (LysoProbes) for lysosomal labeling and trackingSci. Rep.58576(2015)

Chemical Properties of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

Cas No. 68733-20-0 SDF
Canonical SMILES O=C(C)O[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1
Formula C14H19N3O9 M.Wt 373.3
الذوبان DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:3): 0.25mg/mL,DMSO: 15mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6788 mL 13.3941 mL 26.7881 mL
5 mM 0.5358 mL 2.6788 mL 5.3576 mL
10 mM 0.2679 mL 1.3394 mL 2.6788 mL
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In vivo Formulation Calculator (Clear solution) of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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