الصفحة الرئيسية>>(±)14(15)-DiHET

(±)14(15)-DiHET (Synonyms: (±)14,15-DiHETrE,(±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid)

رقم الكتالوجGC26858

(±)14(15)-DiHET is the urinary metabolite of (±)14(15)-EET which has been documented by GC-MS to be elevated in pregnancy-induced hypertension.

Products are for research use only. Not for human use. We do not sell to patients.

(±)14(15)-DiHET التركيب الكيميائي

الحجم السعر المخزون الكميّة
25µg
134٫00
متوفر
50µg
255٫00
متوفر
100µg
480٫00
متوفر
250µg
1061٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description of (±)14(15)-DiHET

(±)14(15)-DiHET is the urinary metabolite of (±)14(15)-EET which has been documented by GC-MS to be elevated in pregnancy-induced hypertension.

References:

1. Catella, F., Lawson, J.A., Fitzgerald, D.J., et alEndogenous biosynthesis of arachidonic acid epoxides in humans: Increased formation in pregnancy-induced hypertension. Proc. Natl. Acad. Sci. USA 87(15), 5893-5897 (1990).

Chemical Properties of (±)14(15)-DiHET

Cas No. SDF
المرادفات (±)14,15-DiHETrE,(±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid
Canonical SMILES CCCCC[C@@H](O)[C@H](O)C/C=C\C/C=C\C/C=C\CCCC(O)=O
Formula C20H34O4 M.Wt 338.5
الذوبان DMF: 50 mg/ml, DMSO: 50 mg/ml Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (±)14(15)-DiHET

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.9542 mL 14.771 mL 29.5421 mL
5 mM 0.5908 mL 2.9542 mL 5.9084 mL
10 mM 0.2954 mL 1.4771 mL 2.9542 mL
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In vivo Formulation Calculator (Clear solution) of (±)14(15)-DiHET

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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