الصفحة الرئيسية>>Signaling Pathways>> GPCR/G protein>> Adrenergic Receptor>>(±)-Clorprenaline-d7

(±)-Clorprenaline-d7 (Synonyms: Isoprophenamine-d7)

رقم الكتالوجGC46283

A neuropeptide with diverse biological activities

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(±)-Clorprenaline-d7 التركيب الكيميائي

Cas No.: 2748354-86-9

الحجم السعر المخزون الكميّة
1 mg
272٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of (±)-Clorprenaline-d7

(±)-Clorprenaline-d7 is intended for use as an internal standard for the quantification of clorprenaline by GC- or LC-MS. Clorprenaline is a β2-adrenergic receptor agonist.1 It reverses pilocarpine-induced constriction of isolated guinea pig trachea, rabbit lung, and bronchi of pithed dogs.2 It has been detected in pork, beef, mutton, and chicken muscle food samples by UPLC-Q-orbitrap-HRMS.1 Formulations containing clorprenaline have been used as partitioning agents and growth promoters in livestock.

1.Guo, C., Shi, F., Gong, L., et al.Ultra-trace analysis of 12 β2-agonists in pork, beef, mutton and chicken by ultrahigh-performance liquid-chromatography-quadrupole-orbitrap tandem mass spectrometryJ. Pharm. Biomed. Anal.107526-534(2015) 2.Powell, C.E., Gibson, W.R., and Swanson, E.E.The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); A bronchodilatorJ. Am. Pharm. Assoc.45(12)785-787(1956)

Chemical Properties of (±)-Clorprenaline-d7

Cas No. 2748354-86-9 SDF
المرادفات Isoprophenamine-d7
Canonical SMILES ClC1=C(C(O)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C=CC=C1
Formula C11H9ClD7NO M.Wt 220.7
الذوبان Chloroform: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (±)-Clorprenaline-d7

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.531 mL 22.6552 mL 45.3104 mL
5 mM 0.9062 mL 4.531 mL 9.0621 mL
10 mM 0.4531 mL 2.2655 mL 4.531 mL
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In vivo Formulation Calculator (Clear solution) of (±)-Clorprenaline-d7

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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