الصفحة الرئيسية>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Potassium Channel>>(-)-[3R,4S]-Chromanol 293B

(-)-[3R,4S]-Chromanol 293B

رقم الكتالوجGC14044

(-) - [3R ، 4S] -Chromanol 293B هو مثبط فعال وانتقائي للمكون البطيء للمقوم المتأخر K+ الحالي (IKs).

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(-)-[3R,4S]-Chromanol 293B التركيب الكيميائي

Cas No.: 163163-24-4

الحجم السعر المخزون الكميّة
10mg
287٫00
Ship Within 7 Days
50mg
1210٫00
Ship Within 7 Days

Tel:(909) 407-4943 Email: sales@glpbio.com


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  • GlpBio Citations

    GlpBio Citations
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Sample solution is provided at 25 µL, 10mM.

Chemical Properties of (-)-[3R,4S]-Chromanol 293B

Cas No. 163163-24-4 SDF
Chemical Name N-((3R,4S)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-methylethanesulfonamide
Canonical SMILES O[C@@H](C(C)(C)OC1=C2C=C(C#N)C=C1)[C@H]2N(C)S(=O)(CC)=O
Formula C15H20N2O4S M.Wt 324.39
الذوبان <32.44mg/ml in ethanol; <32.44mg/ml in DMSO Storage Store at RT
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (-)-[3R,4S]-Chromanol 293B

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.0827 mL 15.4135 mL 30.8271 mL
5 mM 0.6165 mL 3.0827 mL 6.1654 mL
10 mM 0.3083 mL 1.5414 mL 3.0827 mL
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In vivo Formulation Calculator (Clear solution) of (-)-[3R,4S]-Chromanol 293B

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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