الصفحة الرئيسية>>Signaling Pathways>> Tyrosine Kinase>> VEGFR>>4SC-203

4SC-203

رقم الكتالوجGC63805

4SC-203 هو مثبط قوي متعدد للكيناز مع نشاط محتمل لمضادات الأورام4SC-203 انتقائيًا FLT3 / STK1 ، وأشكال FLT3 المتحولة ، و VEGFRs

Products are for research use only. Not for human use. We do not sell to patients.

4SC-203 التركيب الكيميائي

Cas No.: 895533-09-2

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
255٫00
متوفر
1mg
75٫00
متوفر
5mg
180٫00
متوفر
10mg
288٫00
متوفر
25mg
486٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

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Sample solution is provided at 25 µL, 10mM.

Description of 4SC-203

4SC-203 is a potent multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively FLT3/STK1, FLT3 mutated forms, and VEGFRs[1].

[1]. A multikinase inhibitor with potential antineoplastic activity. Multikinase inhibitor

Chemical Properties of 4SC-203

Cas No. 895533-09-2 SDF
Formula C33H38N8O4S M.Wt 642.77
الذوبان DMSO : 125 mg/mL (194.47 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 4SC-203

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.5558 mL 7.7788 mL 15.5577 mL
5 mM 0.3112 mL 1.5558 mL 3.1115 mL
10 mM 0.1556 mL 0.7779 mL 1.5558 mL
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In vivo Formulation Calculator (Clear solution) of 4SC-203

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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