الصفحة الرئيسية>>Signaling Pathways>> TGF-β / Smad Signaling>> PKC>>Aprinocarsen sodium

Aprinocarsen sodium (Synonyms: ISIS 3521 sodium)

رقم الكتالوجGC68679

أبرينوكارسين (ISIS 3521) صوديوم، هو مثبط نوكليوتيدات الراجعة القصيرة والخاص ببروتين كيناز C-α (PKC-α). أبرينوكارسين صوديوم هو عبارة عن سلسلة من 20 نُكْلِئِديَّات قادرة على تحفُّز تمايل الخلاية والانقسام. يستطيع أبرینکارسین صودیم إیقاف نماء خلایای سرطان الإنسان في جهاز المختبر. لذلك فإن أبرینکارسین صودیم له قدرٌ كبيرٌ في التشخیص والعلاج من سرطان الإنسان.

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Aprinocarsen sodium التركيب الكيميائي

Cas No.: 331257-53-5

الحجم السعر المخزون الكميّة
1mg
72٫00
متوفر
5mg
180٫00
متوفر
10mg
266٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Chemical Properties of Aprinocarsen sodium

Cas No. 331257-53-5 SDF
المرادفات ISIS 3521 sodium
Formula C196H230N68Na19O105P19S19 M.Wt 6852.85
الذوبان H2O : 100 mg/mL (14.59 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Aprinocarsen sodium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.1459 mL 0.7296 mL 1.4592 mL
5 mM 0.0292 mL 0.1459 mL 0.2918 mL
10 mM 0.0146 mL 0.073 mL 0.1459 mL
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In vivo Formulation Calculator (Clear solution) of Aprinocarsen sodium

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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