Mast Cell Degranulating Peptide HR-2 |
| رقم الكتالوجGC36547 |
الببتيد HR-2 المتحلل للخلايا البدينة ، وهو ببتيد خطي مكون من 14 ذرة معزولة من سم الزنبور العملاق فيسبا أورينتاليس ، قادر على تحلل الخلايا البدينة وبالتالي إطلاق الهيستامين
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Cas No.: 80388-04-1
Sample solution is provided at 25 µL, 10mM.
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Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release[1].
[1]. Tu?chibaev MU, et al. [Low molecular weight peptides from the venom of the giant hornet Vespa orientalis. Structureand function]. Biokhimiia. 1988 Feb;53(2):219-26.
| Cas No. | 80388-04-1 | SDF | |
| Formula | C77H135N17O14 | M.Wt | 1523 |
| الذوبان | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 0.6566 mL | 3.283 mL | 6.566 mL |
| 5 mM | 0.1313 mL | 0.6566 mL | 1.3132 mL |
| 10 mM | 0.0657 mL | 0.3283 mL | 0.6566 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
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- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
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