الصفحة الرئيسية>>Signaling Pathways>> Cardiovascular>> Myocardial Contractility>>Hydroxydehydro Nifedipine Carboxylate

Hydroxydehydro Nifedipine Carboxylate

رقم الكتالوجGC49250

A metabolite of nifedipine

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Hydroxydehydro Nifedipine Carboxylate التركيب الكيميائي

Cas No.: 34783-31-8

الحجم السعر المخزون الكميّة
2.5 mg
385٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.

Description of Hydroxydehydro Nifedipine Carboxylate

Hydroxydehydro nifedipine carboxylate is a metabolite of nifedipine .1

1.Roosemalen, M.C.M., Soons, P.A., Funaki, T., et al.High-performance liquid chromatographic determination of the polar metabolites of nifedipine in plasma, blood and urineJ. Chromatogr.565(1-2)516-522(1991)

Chemical Properties of Hydroxydehydro Nifedipine Carboxylate

Cas No. 34783-31-8 SDF
Canonical SMILES O=C(OC)C1=C(C2=C([N+]([O-])=O)C=CC=C2)C(C(O)=O)=C(CO)N=C1C
Formula C16H14N2O7 M.Wt 346.3
الذوبان DMSO: slightly soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Hydroxydehydro Nifedipine Carboxylate

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8877 mL 14.4383 mL 28.8767 mL
5 mM 577.5 μL 2.8877 mL 5.7753 mL
10 mM 288.8 μL 1.4438 mL 2.8877 mL
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In vivo Formulation Calculator (Clear solution) of Hydroxydehydro Nifedipine Carboxylate

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Hydroxydehydro Nifedipine Carboxylate

Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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