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Nepinalone hydrochloride

رقم الكتالوجGC61880

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Nepinalone hydrochloride التركيب الكيميائي

Cas No.: 22443-55-6

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
376٫20
متوفر
5 mg
342٫00
متوفر
10 mg
576٫00
متوفر
50 mg
1620٫00
متوفر
100 mg
2520٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

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Sample solution is provided at 25 µL, 10mM.

Description of Nepinalone hydrochloride

Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity[1].

References:
[1]. Braga, et al. AZIONE ANTITOSSE DEGLI ISOMERI LEVO E DESTRO DELL NEPINALONE NEI CONFRONTI DEL RACEMO NELLA CAVIA STIMOLATA CON ACIDO CITRICO. GIMT - Giornale Italiano delle Malattie del Torace, 47(1-2), 17-22.

Chemical Properties of Nepinalone hydrochloride

Cas No. 22443-55-6 SDF
Canonical SMILES [H]Cl.CC1(C2=CC=CC=C2CCC1=O)CCN3CCCCC3
Formula C18H26ClNO M.Wt 307.86
الذوبان DMSO : 250 mg/mL (812.06 mM) Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Nepinalone hydrochloride

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.2482 mL 16.2411 mL 32.4823 mL
5 mM 0.6496 mL 3.2482 mL 6.4965 mL
10 mM 0.3248 mL 1.6241 mL 3.2482 mL
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In vivo Formulation Calculator (Clear solution) of Nepinalone hydrochloride

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Nepinalone hydrochloride

Average Rating: 5 ★★★★★ (Based on Reviews and 6 reference(s) in Google Scholar.)

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