Oxamyl (Synonyms: NSC 379588) |
| رقم الكتالوجGC47847 |
A carbamate pesticide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 23135-22-0
Sample solution is provided at 25 µL, 10mM.
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Oxamyl is a carbamate pesticide and an inhibitor of acetylcholinesterase (AChE; IC50 = 1.67 μM for C. gigas enzyme).1 It is nematocidal, decreasing the number of P. penetrans and M. hapla per gram of alfalfa (M. sativa) root when applied to seeds at a concentration of 50 mg/ml.2 Oxamyl (50 and 100 μg/ml) is also toxic to citrus nematode (T. semipenetrans) larvae.3 In vivo, oxamyl (2.1 and 3.5 mg/kg) inhibits plasma and brain AChE, as well as liver glucose-6-phosphatase and succinic acid dehydrogenase, and reduces body weight gain in rats.4 Formulations containing oxamyl have been used to control nematode infestation of field crops.
1.Anguiano, G.A., Amador, A., Moreno-Legorreta, M., et al.Effects of exposure to oxamyl, carbofuran, dichlorvos, and lindane on acetylcholinesterase activity in the gills of the Pacific oyster Crassostrea gigasEnviron. Toxicol.25(4)327-332(2010) 2.Townshend, J.L., and Chiba, M.Control of Pratylenchus penetrans and Meloidogyne hapla and yield response of alfalfa due to oxamyl seed treatmentsJ. Nematol.19(4)454-458(1987) 3.Baines, R.C., and Small, R.H.Effects of oxamyl on the citrus nematode, Tylenchulus semipenetrans, and on infection of sweet orangeJ. Nematol.8(2)122-130(1976) 4.Fayez, V., and Kilgore, W.W.Acute toxic effects of oxamyl in the ratFundam. Appl. Toxicol.18(1)155-159(1992)
| Cas No. | 23135-22-0 | SDF | |
| المرادفات | NSC 379588 | ||
| Canonical SMILES | CN(C)C(/C(SC)=N/OC(NC)=O)=O | ||
| Formula | C7H13N3O3S | M.Wt | 219.3 |
| الذوبان | Chloroform: Slightly Soluble,Methanol: Slightly Soluble | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 4.56 mL | 22.7998 mL | 45.5996 mL |
| 5 mM | 912 μL | 4.56 mL | 9.1199 mL |
| 10 mM | 456 μL | 2.28 mL | 4.56 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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