(R)-3-Hydroxybutanoic acid |
| رقم الكتالوجGC30210 |
(R) -3-Hydroxybutanoic acid هو مستقلب ، ويتم تحويله من حمض الخليك المحفز بواسطة 3-hydroxybutyrate dehydrogenase
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 625-72-9
Sample solution is provided at 25 µL, 10mM.
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(R)-3-Hydroxybutanoic acid is a polyhydroxybutyrate (PHB) monomer that can be reacted with various hydroxy fatty acids to prepare copolymers with industrial and pharmaceutical uses[1, 2, 3]. (R)-3-Hydroxybutanoic acid is a metabolite obtained from ethyl acetate catalyzed by 3-hydroxybutyrate dehydrogenase[4]. (R)-3-Hydroxybutanoic acid can be used as a nutritional source and a precursor of vitamins, antibiotics and pheromones[5].
References:
[1] Kok F, Hasirci V. Polyhydroxybutyrate and its copolymers: Applications in the medical field[J]. Tissue Engineering and Novel Delivery Systems. 1th ed. Arcel Dekker: New York, NY, USA, 2004: 543-562.
[2] Md. Iqbal N, Amirul A A. Synthesis of P (3HB‐co‐4HB) copolymer with target‐specific 4HB molar fractions using combinations of carbon substrates[J]. Journal of Chemical Technology & Biotechnology, 2014, 89(3): 407-418.
[3] Kundu P P, Nandy A, Mukherjee A, et al. Polyhydroxyalkanoates: Microbial synthesis and applications[J]. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials; CRC Press: Boca Raton, FL, USA, 2015, 11: 10444.
[4] Yañez L, Conejeros R, Vergara-Fernández A, et al. Beyond intracellular accumulation of polyhydroxyalkanoates: chiral hydroxyalkanoic acids and polymer secretion[J]. Frontiers in Bioengineering and Biotechnology, 2020, 8: 248.
[5] Ren Q, Grubelnik A, Hoerler M, et al. Bacterial poly (hydroxyalkanoates) as a source of chiral hydroxyalkanoic acids[J]. Biomacromolecules, 2005, 6(4): 2290-2298.
| Cas No. | 625-72-9 | SDF | |
| Canonical SMILES | C[C@@H](O)CC(O)=O | ||
| Formula | C4H8O3 | M.Wt | 104.1 |
| الذوبان | Water : ≥ 25 mg/mL (240.15 mM) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 9.6061 mL | 48.0307 mL | 96.0615 mL |
| 5 mM | 1.9212 mL | 9.6061 mL | 19.2123 mL |
| 10 mM | 0.9606 mL | 4.8031 mL | 9.6061 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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