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الصفحة الرئيسية >> Signaling Pathways >> Cardiovascular >> Atherosclerosis

Atherosclerosis

منتجات لـ نبسب؛ Atherosclerosis

  1. القط. رقم اسم المنتج بيانات
  2. GC48283 α-Linolenic Acid-d14

    ALAd14

     An internal standard for the quantification of αLinolenic acid α-Linolenic Acid-d14 Chemical Structure
  3. GC40467 (±)11-HETE

    (±)11-Hydroxyeicosatetraenoic Acid

     (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  4. GC41649 (±)13-HODE cholesteryl ester (±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)13-HODE cholesteryl ester Chemical Structure
  5. GC41666 (±)9-HODE cholesteryl ester (±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)9-HODE cholesteryl ester Chemical Structure
  6. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  7. GC46494 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-PC

    18:0/20:4-d11-PC, PC(18:0/20:4-d11), SAPC-d11, 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-Phosphocholine

     A neuropeptide with diverse biological activities 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-PC Chemical Structure
  8. GC46496 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC

    18:0/20:4-d8-PC, PC(18:0/20:4-d8), SAPCd8, 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-Phosphocholine

     An internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC Chemical Structure
  9. GC41893 13(R)-HODE cholesteryl ester 13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 13(R)-HODE cholesteryl ester Chemical Structure
  10. GC41895 13(S)-HODE cholesteryl ester 13(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 13(S)-HODE cholesteryl ester Chemical Structure
  11. GC41897 13(S)-HOTrE 13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. 13(S)-HOTrE Chemical Structure
  12. GC49671 2,3-Oxidosqualene

    (3R,S)-Oxidosqualene, Squalene 2,3-oxide

     An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  13. GC41614 24-dehydro Cholesterol

    Desmosterol

    24-ديهيدروكولسترول هو جزيء مشابه للكولسترول.

     24-dehydro Cholesterol Chemical Structure
  14. GC46243 24-dehydro Cholesterol-d6

    Desmosterol-d6

     An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6 Chemical Structure
  15. GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol 25-hydroxy Cholesterol-d6 Chemical Structure
  16. GC48449 28-(Poc-amino)betulin 28-(Poc-amino)betulin Chemical Structure
  17. GC42411 4-hydroxy Nonenal Alkyne

    Click Tag 4HNE Alkyne

    4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.

     4-hydroxy Nonenal Alkyne Chemical Structure
  18. GC40053 5α,6α-epoxy Cholestanol

    NSC 18176

     An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol Chemical Structure
  19. GC40418 5β,6β-epoxy Cholestanol

    NSC 148940

    5β,6β-epoxy Cholestanol is an oxidative metabolite of cholesterol that is formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond.

     5β,6β-epoxy Cholestanol Chemical Structure
  20. GC45357 5-Chlorouracil   5-Chlorouracil Chemical Structure
  21. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  22. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxycholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

     7α-hydroxy Cholesterol-d7 Chemical Structure
  23. GC46241 7-keto Cholesterol-d7

    7-oxo Cholesterol-d7

    7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL

     7-keto Cholesterol-d7 Chemical Structure
  24. GC49443 7α-hydroxy Cholesterol

    7β-Hydroxycholesterol, 7β-OHC

     7α-hydroxy Cholesterol هو أكسيد كولسترول ويتكون من الأكسدة الأنزيمية وغير الأنزيمية. 7α-hydroxy Cholesterol Chemical Structure
  25. GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(R)-HODE cholesteryl ester Chemical Structure
  26. GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. 9(S)-HODE Chemical Structure
  27. GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(S)-HODE cholesteryl ester Chemical Structure
  28. GC49784 AZD 2716 An sPLA2 inhibitor AZD 2716 Chemical Structure
  29. GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. Azelaoyl PAF Chemical Structure
  30. GC46912 Beauveriolide III Beauveriolide III هو مثبط لتكوين قطيرات الدهون في الضامة الفأرية Beauveriolide III Chemical Structure
  31. GC45390 Benazepril Acyl-β-D-Glucuronide

    Benazapril Glucuronide

       Benazepril Acyl-β-D-Glucuronide Chemical Structure
  32. GC42924 Beraprost (sodium salt)

    ML 1129, Procyclin, TRK 100

     Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. Beraprost (sodium salt) Chemical Structure
  33. GC42994 Butanoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes. Butanoyl PAF Chemical Structure
  34. GC43136 Campestanol

    24-Methyl-5α-cholestan-3β-ol

     Campestanol هو فيتوستيرول يمكن العثور عليه في الأطعمة النباتية Campestanol Chemical Structure
  35. GC43160 CAY10485

    3,4dihydroxy Hydrocinnamic acid (LAspartic acid dibenzyl ester) amide

     Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 Chemical Structure
  36. GC41636 CAY10487

    3,4Dihydrocinnamic Acid (Lalanine methyl ester) amide

     The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 Chemical Structure
  37. GC40203 Cholesterol-d6

    Provitamin D-d6

    Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.

     Cholesterol-d6 Chemical Structure
  38. GC47085 Cholesterol-d7

    Provitamin D-d7

     An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  39. GC43255 Cholesteryl Arachidonate Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland. Cholesteryl Arachidonate Chemical Structure
  40. GC19433 Cholesteryl Heptadecanoate

    Cholesteryl Margarate, Heptadecanoic Acid cholesteryl ester, Margaric Acid cholesteryl ester

     Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. Cholesteryl Heptadecanoate Chemical Structure
  41. GC43260 Cholesteryl Linoleate Hydroperoxides Cholesteryl linoleate hydroperoxides are derived from the autoxidation of cholesteryl linoleate and contain a mixture of racemic 9- and 13-HpODE cholesteryl esters. Cholesteryl Linoleate Hydroperoxides Chemical Structure
  42. GC43263 Cholesteryl Stearate

    18:0 CE, 18:0 Cholesterol ester, CE(18:0), Cholesterol Stearate, NSC 59693

     Cholesteryl stearate is a cholesterol ester. Cholesteryl Stearate Chemical Structure
  43. GC47135 CV-6209-d5 A neuropeptide with diverse biological activities CV-6209-d5 Chemical Structure
  44. GC46134 Dityrosine (hydrochloride)

    Bityrosine, o,o-Ditryosine

     A neuropeptide with diverse biological activities Dityrosine (hydrochloride) Chemical Structure
  45. GC91933 E17241

    4-(1,3-Dithiolan-2-yl)-N-(3-hydroxypyridin-2-yl)benzamide

     ويُحفِّز E17241 التعبير ABCA1، الذي يشفِّر المورِّثات الناقلة 1 التي تربط ATP-الكاسيت ؛ العائلة الفرعية A (ABCA1). E17241 Chemical Structure
  46. GC52193 Eptifibatide Eptifibatide عبارة عن سباعي ببتيد دوري ، يعمل كمضاد تنافسي لمستقبلات بروتين سكري الصفائح الدموية المنشطة IIb / IIIa ، مع نشاط مضاد للصفائح الدموية Eptifibatide Chemical Structure
  47. GC33760 ETC-1002 (ESP-55016)

    Bempedoic Acid, ESP-55016

     ETC-1002 (ESP-55016) (ETC-1002) هو مثبط لياز سيترات ATP (ACL). ETC-1002 (ESP-55016) Chemical Structure
  48. GC92113 FNIII14 (sodium salt)

    FNIII14-2

     FNIII14 (sodium salt) هو مثبط للالتصاق الخلوي و ببتيد مشتق من تكرار النوع الثالث عشر، الذي هو جزء من مجال ربط الهيبارين 2، من فيبرونيكتين الإنسان والفأر والفأر. FNIII14 (sodium salt) Chemical Structure
  49. GC47397 Gemfibrozil-d6

    CI-719-d6

     An internal standard for the quantification of gemfibrozil Gemfibrozil-d6 Chemical Structure
  50. GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide Gliclazide-d4 Chemical Structure
  51. GC18788 Graphislactone A Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. Graphislactone A Chemical Structure
  52. GC46155 H-Ile-Pro-Pro-OH (trifluoroacetate salt)

    IPP

     A neuropeptide with diverse biological activities H-Ile-Pro-Pro-OH (trifluoroacetate salt) Chemical Structure
  53. GC47438 H-Val-Pro-Pro-OH (trifluoroactetate salt)

    VPP

     A neuropeptide with diverse biological activities H-Val-Pro-Pro-OH (trifluoroactetate salt) Chemical Structure
  54. GC43803 HA-1077 (hydrochloride)

    Fasudil

     Fasudil (HA-1077؛ AT877) ثنائي هيدروكلوريد هو مثبط RhoA / ROCK غير محدد وله أيضًا تأثير مثبط على كينازات البروتين ، مع Ki 0.33 μ ؛ M لـ ROCK1 ، IC50s من 0.158 μ ؛ M و 4.58 &8888956 ؛ M و 4.58 &8888956 ؛ ؛ M ، 1.650 μ ؛ M لـ ROCK2 و PKA ، PKC ، PKG ، على التوالي. HA-1077 (هيدروكلوريد) هو أيضًا مضاد فعال لقناة Ca2+ وموسع للأوعية. HA-1077 (hydrochloride) Chemical Structure
  55. GC45469 Hexacosanoic Acid-d4   Hexacosanoic Acid-d4 Chemical Structure
  56. GC49496 Homocitrulline-d3

    ε-Carbamyllysine-d3, L-ε-Amino-Carbamoyl-Lysine-d3

     An internal standard for the quantification of homocitrulline Homocitrulline-d3 Chemical Structure
  57. GC43997 KDdiA-PC KDdiA-PC هو نوع من LDL المؤكسد (oxLDL) ، وهو يجند لمستقبل الزبال الضامة CD36 KDdiA-PC Chemical Structure
  58. GC44011 KOdiA-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. KOdiA-PC Chemical Structure
  59. GC52497 Lactosylceramide (porcine RBC)

    LacCer

     A sphingolipid Lactosylceramide (porcine RBC) Chemical Structure
  60. GC40142 Lactosylceramides (bovine buttermilk)

    LacCer

     Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid. Lactosylceramides (bovine buttermilk) Chemical Structure
  61. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  62. GC44093 Lutein

    E 161b, Xanthophyll

     Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina. Lutein Chemical Structure
  63. GC18241 Lysophosphatidylcholines

    ​Lyso-Lecithins (egg)

    Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfers the fatty acid to cholesterol.

     Lysophosphatidylcholines Chemical Structure
  64. GC49486 Meglutol-d3

    Dicrotalic Acid-d3, 3-hydroxy 3-methyl Glutaric Acid-d3, HMG-d3, 3-methyl-3-Hydroxyglutaric Acid-d3, Medroglutaric Acid-d3, 3-hydroxy-3-Methylglutaric Acid-d3

     An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  65. GC44180 Methylcarbamyl PAF C-16 Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. Methylcarbamyl PAF C-16 Chemical Structure
  66. GC40624 MMP-3 Inhibitor VIII

    Matrix Metalloproteinase-3 Inhibitor VIII, Stromelysin-1 Inhibitor VIII

     Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 Inhibitor VIII Chemical Structure
  67. GC18616 MMP-8 Inhibitor I

    Matrix Metalloproteinase-8 Inhibitor I

     MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  68. GC46175 MOTS-c (human) (trifluoroacetate salt)

    Mitochondrial open reading frame of the 12S rRNA-c

     A neuropeptide with diverse biological activities MOTS-c (human) (trifluoroacetate salt) Chemical Structure
  69. GC48418 N-(2-Poc-ethyl)betulin amide N-(2-Poc-ethyl)betulin amide Chemical Structure
  70. GC20172 N-Isopropylphthalimide N-Isopropylphthalimide Chemical Structure
  71. GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Osteocalcin (1-49) (human) (trifluoroacetate salt) Chemical Structure
  72. GC44573 PAz-PC

    Azelaoyl PC, 1Palmitoyl2Azelaoyl PC

     Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. PAz-PC Chemical Structure
  73. GC44616 PGPC

    1-Palmitoyl-2-glutaryl phosphatidylcholine

    PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress.

     PGPC Chemical Structure
  74. GC44633 Phosphatidylserines (bovine)

    PtdSers (bovine)

     Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (bovine) Chemical Structure
  75. GC18522 Phosphatidylserines (sodium salt)

    L-α-Phosphatidylserine, PtdSer (Soy), Soy PS

     Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (sodium salt) Chemical Structure
  76. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  77. GC90490 PMX-53 (trifluoroacetate salt)

    مثبط مستقبل C5a

     PMX-53 (trifluoroacetate salt) Chemical Structure
  78. GC44669 POV-PC

    2(5oxovaleryl) Phosphatidylcholine

     Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. POV-PC Chemical Structure
  79. GC47970 Prednisone-d7

    1,2-Dehydrocortisone-d7

     A neuropeptide with diverse biological activities Prednisone-d7 Chemical Structure
  80. GC49107 Rosuvastatin lactone

    (+)-Rosuvastatin lactone, Rosuvastatin-5S-lactone, RSTL

     The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  81. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  82. GC44910 Sodium Hydrogen Sulfide (hydrate)

    NaHS, NSC 158264, Sodium Hydrosulfide

     Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) Chemical Structure
  83. GC61286 SP-8356 SP-8356 Chemical Structure
  84. GC91042 Tauro-Obeticholic Acid (sodium salt)

    متابوليت نشط لحمض أوبيتيكوليك.

     Tauro-Obeticholic Acid (sodium salt) Chemical Structure
  85. GC45057 TIQ-A TIQ-A هو مثبط فعال لـ TNKS (poly-ART ، PARP) ، مع IC 50 من 24 نانومتر لـ TNKS2 TIQ-A Chemical Structure
  86. GC48196 trans-Vaccenic Acid-d13

    C18:1(11E)-d13, C18:1 n-7-d13, trans-11-Octadecenoic Acid-d13

     A neuropeptide with diverse biological activities trans-Vaccenic Acid-d13 Chemical Structure
  87. GC48206 Trimethylamine-d9 N-oxide

    TMAO-d9

     An internal standard for the quantification of trimethylamine N-oxide Trimethylamine-d9 N-oxide Chemical Structure
  88. GC45129 Urocortin (human) (trifluoroacetate salt) Urocortin is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF, urocortin II, urocortin III, frog sauvagine, and piscine urotensin I. Urocortin (human) (trifluoroacetate salt) Chemical Structure
  89. GC91136 XY-4

    محفز لـ PPARγ

     XY-4 Chemical Structure

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