Cholesterol Metabolism
منتجات لـ نبسب؛ Cholesterol Metabolism
- القط. رقم اسم المنتج بيانات
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GC49690
(3R,5R)-Rosuvastatin (calcium salt)
A potential impurity found in bulk preparations of rosuvastatin
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GC40452
15(S)-HETE MaxSpec® Standard
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
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GC40457
19(R)-HETE
19(R)-Hydroxyeicosatetraenoic Acid
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. -
GC40417
19-hydroxy Cholesterol
19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol.
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GC49671
2,3-Oxidosqualene
(3R,S)-Oxidosqualene, Squalene 2,3-oxide
An intermediate in the biosynthesis of sterols -
GC41614
24-dehydro Cholesterol
Desmosterol
24-ديهيدروكولسترول هو جزيء مشابه للكولسترول.
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GC46243
24-dehydro Cholesterol-d6
Desmosterol-d6
An internal standard for the quantification of 24-dehydro cholesterol -
GC46528
25-hydroxy Cholesterol-d6
An internal standard for the quantification of 25hydroxy cholesterol
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GC48449
28-(Poc-amino)betulin
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GC62033
3α-Hydroxy pravastatin sodium
3α-Isopravastatin, R-416
3α ؛-هيدروكسي برافاستاتين الصوديوم هو المستقلب الرئيسي للبرافاستاتين. -
GC40799
3-hydroxy-3-Methylglutaric anhydride
Dicrotalic anhydride, HMG anhydride
The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. -
GC42405
4-hydroxy Atorvastatin (calcium salt)
p-hydroxy Atorvastatin, para-hydroxy Atorvastatin
4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. -
GC18425
4-hydroxy Atorvastatin lactone
p-hydroxy Atorvastatin lactone, para-hydroxy Atorvastatin lactone
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
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GC40535
6,15-diketo-13,14-dihydro Prostaglandin F1α
6,15diketo13,14dihydro PGF1α
6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. -
GC46889
Atorvastatin (calcium salt hydrate)
An HMG-CoA reductase inhibitor
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GC49421
Atorvastatin lactone-d5
An internal standard for the quantification of atorvastatin lactone
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GC46890
Atorvastatin-d5 (calcium salt)
An internal standard for the quantification of atorvastatin
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GC46911
Beauveriolide I
Beauveriolide I هو مستقلب للفطريات الممرضة للحشرات Beauveria sp
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GC46912
Beauveriolide III
Beauveriolide III هو مثبط لتكوين قطيرات الدهون في الضامة الفأرية
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GC45390
Benazepril Acyl-β-D-Glucuronide
Benazapril Glucuronide
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GC19530
Brassicasterol
يلعب Brassicasterol ، وهو أحد مستقلبات Ergosterol ، دورًا في التأثير المثبط على تعزيز تسرطن المثانة عبر إشارات الأندروجين
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GC43160
CAY10485
3,4dihydroxy Hydrocinnamic acid (LAspartic acid dibenzyl ester) amide
Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. -
GC40869
CAY10486
4Hydroxycinnamic acid (Lphenylalanine methyl ester) amide
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. -
GC47085
Cholesterol-d7
Provitamin D-d7
An internal standard for the quantification of cholesterol -
GC90700
Dendrogenin A
منظم اختياري لـ LXR ومثبط ChEH
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GC47367
Fluvastatin (sodium salt hydrate)
An HMG-CoA reductase inhibitor
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GC49303
Ganoderic Acid DM
حمض الجانوديريك DM ، ترايتيربينويد طبيعي معزول من غانوديرما لوسيدوم ، يسبب تلف الحمض النووي ، توقف دورة الخلية G1 وموت الخلايا المبرمج في خلايا سرطان الثدي البشرية
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GC43745
Geranyl Pyrophosphate (triammonium salt)
GDP, Geranyl Diphosphate, GPP
جيرانيل بيروفوسفات (ملح ثلاثي الأمونيوم) هو مركب وسيط رئيسي في مسار تخليق الإزوبرنويدات.
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GC45801
Hesperetin-13C-d3
A neuropeptide with diverse biological activities
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GC43883
Hymeglusin
Antibiotic 1233A
Hymeglusin ، كمضاد حيوي فطري β-lactone ، هو مثبط سينثيز HMG-CoA (IC50 = 0.12 ميكرومتر) -
GC49486
Meglutol-d3
Dicrotalic Acid-d3, 3-hydroxy 3-methyl Glutaric Acid-d3, HMG-d3, 3-methyl-3-Hydroxyglutaric Acid-d3, Medroglutaric Acid-d3, 3-hydroxy-3-Methylglutaric Acid-d3
An internal standard for the quantification of meglutol -
GC48418
N-(2-Poc-ethyl)betulin amide
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GC47756
N-desmethyl Rosuvastatin (sodium salt hydrate)
An active metabolite of rosuvastatin
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GC44497
Oleic Acid-2,6-diisopropylanilide
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.
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GC44590
Pellitorine
Pellitorine هو مركب معزول من جذور Piper nigrum. يُظهر Pellitorine أنشطة سامة للخلايا قوية ضد خطوط الخلايا HL60 و MCT-7. يتمتع Pellitorine بإمكانية البحث عن أمراض السرطان.
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GC49340
Pitavastatin lactone-d4
An internal standard for the quantification of pitavastatin lactone
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GC40220
Pravastatin-d3 (sodium salt)
Pravastatin-d3 (CS-514-d3) ملح الصوديوم هو الديوتيريوم المسمى ملح الصوديوم Pravastatin.
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GC49107
Rosuvastatin lactone
(+)-Rosuvastatin lactone, Rosuvastatin-5S-lactone, RSTL
The lactone form of rosuvastatin -
GC48060
Rosuvastatin-d6 (sodium salt)
An internal standard for the quantification of rosuvastatin
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GC49333
SH-42
مثبط لإنزيم DHCR24
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GC50196
Simvastatin - d6
SVA-d6
Deuterated simvastatin -
GC45017
Terpendole C
يُظهر Terpendole C ، الذي تنتجه Albophoma yamanashiensis ، نشاطًا مثبطًا قويًا ضد acyl-CoA: الكوليسترول acyltransferase (ACAT)
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GC45060
TMP-153
Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues.
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GC45090
Triparanol
MER-29, NSC 65345
Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol.