Immunology/Inflammation
The immune and inflammation-related pathway including the Toll-like receptors pathway, the B cell receptor signaling pathway, the T cell receptor signaling pathway, etc.
Toll-like receptors (TLRs) play a central role in host cell recognition and responses to microbial pathogens. TLR4 initially recruits TIRAP and MyD88. MyD88 then recruits IRAKs, TRAF6, and the TAK1 complex, leading to early-stage activation of NF-κB and MAP kinases [1]. TLR4 is endocytosed and delivered to intracellular vesicles and forms a complex with TRAM and TRIF, which then recruits TRAF3 and the protein kinases TBK1 and IKKi. TBK1 and IKKi catalyze the phosphorylation of IRF3, leading to the expression of type I IFN [2].
BCR signaling is initiated through ligation of mIg under conditions that induce phosphorylation of the ITAMs in CD79, leading to the activation of Syk. Once Syk is activated, the BCR signal is transmitted via a series of proteins associated with the adaptor protein B-cell linker (Blnk, SLP-65). Blnk binds CD79a via non-ITAM tyrosines and is phosphorylated by Syk. Phospho-Blnk acts as a scaffold for the assembly of the other components, including Bruton’s tyrosine kinase (Btk), Vav 1, and phospholipase C-gamma 2 (PLCγ2) [3]. Following the assembly of the BCR-signalosome, GRB2 binds and activates the Ras-guanine exchange factor SOS, which in turn activates the small GTPase RAS. The original RAS signal is transmitted and amplified through the mitogen-activated protein kinase (MAPK) pathway, which including the serine/threonine-specific protein kinase RAF followed by MEK and extracellular signal related kinases ERK 1 and 2 [4]. After stimulation of BCR, CD19 is phosphorylated by Lyn. Phosphorylated CD19 activates PI3K by binding to the p85 subunit of PI3K and produce phosphatidylinositol-3,4,5-trisphosphate (PIP3) from PIP2, and PIP3 transmits signals downstream [5].
Central process of T cells responding to specific antigens is the binding of the T-cell receptor (TCR) to specific peptides bound to the major histocompatibility complex which expressed on antigen-presenting cells (APCs). Once TCR connected with its ligand, the ζ-chain–associated protein kinase 70 molecules (Zap-70) are recruited to the TCR-CD3 site and activated, resulting in an initiation of several signaling cascades. Once stimulation, Zap-70 forms complexes with several molecules including SLP-76; and a sequential protein kinase cascade is initiated, consisting of MAP kinase kinase kinase (MAP3K), MAP kinase kinase (MAPKK), and MAP kinase (MAPK) [6]. Two MAPK kinases, MKK4 and MKK7, have been reported to be the primary activators of JNK. MKK3, MKK4, and MKK6 are activators of P38 MAP kinase [7]. MAP kinase pathways are major pathways induced by TCR stimulation, and they play a key role in T-cell responses.
Phosphoinositide 3-kinase (PI3K) binds to the cytosolic domain of CD28, leading to conversion of PIP2 to PIP3, activation of PKB (Akt) and phosphoinositide-dependent kinase 1 (PDK1), and subsequent signaling transduction [8].
References
[1] Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors[J]. Nature immunology, 2010, 11(5): 373-384.
[2] Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity[J]. Immunity, 2011, 34(5): 637-650.
[3] Packard T A, Cambier J C. B lymphocyte antigen receptor signaling: initiation, amplification, and regulation[J]. F1000Prime Rep, 2013, 5(40.10): 12703.
[4] Zhong Y, Byrd J C, Dubovsky J A. The B-cell receptor pathway: a critical component of healthy and malignant immune biology[C]//Seminars in hematology. WB Saunders, 2014, 51(3): 206-218.
[5] Baba Y, Matsumoto M, Kurosaki T. Calcium signaling in B cells: regulation of cytosolic Ca 2+ increase and its sensor molecules, STIM1 and STIM2[J]. Molecular immunology, 2014, 62(2): 339-343.
[6] Adachi K, Davis M M. T-cell receptor ligation induces distinct signaling pathways in naive vs. antigen-experienced T cells[J]. Proceedings of the National Academy of Sciences, 2011, 108(4): 1549-1554.
[7] Rincón M, Flavell R A, Davis R A. The Jnk and P38 MAP kinase signaling pathways in T cell–mediated immune responses[J]. Free Radical Biology and Medicine, 2000, 28(9): 1328-1337.
[8] Bashour K T, Gondarenko A, Chen H, et al. CD28 and CD3 have complementary roles in T-cell traction forces[J]. Proceedings of the National Academy of Sciences, 2014, 111(6): 2241-2246.
أهداف لـ نبسب؛ Immunology/Inflammation
- Apoptosis(456)
- Cyclic GMP-AMP Synthase(2)
- 5-Lipoxygenase(18)
- TLR(98)
- Papain(1)
- PGDS(1)
- PGE synthase(24)
- SIKs(12)
- IκB/IKK(63)
- AP-1(6)
- KEAP1-Nrf2(44)
- NOD1(1)
- NF-κB(250)
- Interleukin Related(170)
- 15-lipoxygenase(2)
- Others(10)
- Aryl Hydrocarbon Receptor(36)
- CD73(16)
- Complement System(58)
- Galectin(33)
- IFNAR(25)
- NO Synthase(77)
- NOD-like Receptor (NLR)(51)
- STING(110)
- Reactive Oxygen Species(465)
- FKBP(12)
- eNOS(5)
- iNOS(29)
- nNOS(20)
- Glutathione(57)
- Adaptive Immunity(222)
- Allergy(162)
- Arthritis(34)
- Autoimmunity(190)
- Gastric Disease(101)
- Immunosuppressants(39)
- Immunotherapeutics(5)
- Innate Immunity(593)
- Pulmonary Diseases(119)
- Reactive Nitrogen Species(55)
- Specialized Pro-Resolving Mediators(50)
- Reactive Sulfur Species(28)
- BCL6(3)
- CD20(3)
- CD22(0)
- CD28(1)
- PSMA(7)
- FAP(7)
- Nuclear Factor of activated T Cells (NFAT)(1)
- Glycoprotein VI(1)
- Tim3(2)
- Hapten(1)
- Nectin-4(2)
منتجات لـ نبسب؛ Immunology/Inflammation
- القط. رقم اسم المنتج بيانات
-
GC19910
2,2',4,4'-Tetrabromodiphenyl Ether
BDE-47
-
GC19941
DL-Leucic Acid
-
GC50569
NLRP3-IN-2
NLRP3-IN-2 ، ركيزة وسيطة في تخليق الغليبوريد ، تمنع تكوين الجسيم الملتهب NLRP3 في خلايا عضلة القلب ويحد من حجم الاحتشاء بعد نقص تروية عضلة القلب / إعادة ضخه في الفأر ، دون التأثير على استقلاب الجلوكوز
-
GC45194
α-(difluoromethyl)-DL-Arginine
DFMA, RMI 71897
Bacteria synthesize the cellular growth factor putrescine through a number of pathways.
-
GC65446
α-Amyrin acetate
α ؛ - أسيتات الأميرين ، ترايتيربينويد طبيعي ، له نشاط مضاد للالتهابات ، ومضاد للتشنج وتأثير ارتخاء.
-
GC45200
α-CGRP (rat) (trifluoroacetate salt)
Calcitonin Gene-Related Peptide-1 (rat), α-Calcitonin Gene-Related Peptide (rat), CGRP-1 (rat)
α-Calcitonin gene-related peptide (α-CGRP) is a neuropeptide with roles in vasodilation, cardiovascular regulation, and inflammation. -
GC49838
α-Cortolone
20α-Cortolone, NSC 59872
A metabolite of cortisol -
GC48279
α-D-Glucose-1-phosphate (sodium salt hydrate)
α-D-Glc 1-P
An intermediate in glycogen metabolism -
GC52253
α-Enolase (1-19)-biotin Peptide
Enolase-1 (1-19)-biotin
A biotinylated α-enolase peptide -
GC45206
α-GalCer analog 8
α-Galactosylceramide analog 8
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.
-
GC40262
α-Humulene
αCaryophyllene, (±)-αHumulene
α ؛ -Humulene هو مكون رئيسي من Tanacetum vulgare L. -
GC45601
α-Linolenic Acid ethyl ester-d5
ALAEE-d5, Ethyl α-Linolenate-d5, Ethyl Linolenate-d5, LAEE-d5, Linolenic Acid ethyl ester-d5
-
GC48292
α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
α-Melanocyte-stimulating Hormone, Ac-SYSMEHFRWGKPV-NH2
α ؛ -MSH (α ؛ -هرمون تحفيز الخلايا الصغرى) TFA ، وهو ببتيد عصبي داخلي ، وهو ناهض لمستقبل الميلانوكورتين 4 (MC4R) مع أنشطة مضادة للالتهابات وخافض للحرارة. -
GC41499
α-Phellandrene
p-Mentha-1,5-diene, (±)-α-Phellandrene
α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. -
GC63941
α-Solanine
α ؛ - لقد لوحظ أن السولانين ، وهو مكون نشط بيولوجيًا وواحد من الجليكوالكالويدس الستيرويدي الرئيسي في البطاطس ، يثبط النمو ويحفز موت الخلايا المبرمج في الخلايا السرطانية.
-
GC67618
α-Tocopherol phosphate disodium
alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium
α ؛ - توكوفيرول فوسفات (ألفا توكوفيرول فوسفات) ثنائي الصوديوم ، أحد مضادات الأكسدة الواعدة ، يمكن أن يحمي من موت الخلايا الذي يسببه الأشعة فوق البنفسجية الطويلة الموجة ويكسح UVA1 المستحثة بـ ROS في نموذج خلية الجلد. α ؛ - يمتلك ثنائي فوسفات توكوفيرول إمكانات علاجية في تثبيط موت الخلايا المبرمج ويزيد من القدرة المهاجرة للخلايا السلفية البطانية في ظل ظروف ارتفاع الجلوكوز / نقص الأكسجة ويعزز تكوين الأوعية. -
GC70953
α7 nAchR-JAK2-STAT3 agonist 1
α7 nAchR-JAK2-STAT3 agonist 1 هو ناهض قوي α7 nAchR-JAK2-STAT3، بقيمة IC50 0.32 ميكرومتر لأكسيد النتريك (NO).
-
GC49467
β-Aescin
A triterpenoid saponin with diverse biological activities
-
GC70787
β-Aminoarteether
β-Aminoarteether (SM934 القاعدة الحرة) هو مشتق أرتيميسينين نشط عن طريق الفم.
-
GC37999
β-Anhydroicaritin
β ؛ -Anhydroicaritin معزول عن Boswellia carterii Birdware ، له تأثيرات بيولوجية ودوائية مهمة ، مثل مضادات هشاشة العظام وتنظيم هرمون الاستروجين وخصائص مضادة للأورام.
-
GC45225
β-Apooxytetracycline
β-Apo-Oxytetracycline, β-Apoterramycin
β-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. -
GC45226
β-BHC
β-HCH, β-Hexachlorocyclohexane, β-Lindane
β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane. -
GC48920
β-Carboline-1-carboxylic Acid
1-Formic Acid-β-carboline
An alkaloid with diverse biological activities -
GC90496
β-Cortolone
متابوليت للكورتيزول
-
GC66870
β-D-Glucan
β ؛ -D-glucan هو عديد السكاريد الطبيعي غير القابل للهضم والتوافق الحيوي العالي الذي يمكن التعرف عليه بشكل انتقائي من خلال مستقبلات التعرف مثل Dectin-1 والمستقبلات الشبيهة بالتول وكذلك يمكن استيعابها بسهولة بواسطة الفئران أو الضامة البشرية ، والتي من المحتمل أن السمة لتسليم الهدف. β؛ -d-glucan هي وسيلة توصيل معوية للبروبيوتيك.
-
GC48998
β-Defensin-1 (human) (trifluoroacetate salt)
hBD-1
An antimicrobial peptide -
GC48298
β-Defensin-2 (human) (trifluoroacetate salt)
hBD-2
An antimicrobial peptide -
GC45230
β-Defensin-3 (human) (trifluoroacetate salt)
hBD-3
β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. -
GC45231
β-Defensin-4 (human) (trifluoroacetate salt)
hBD-4 (human)
β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. -
GC41623
β-Elemonic Acid
Elemadienonic Acid, 3-Oxotirucallenoic Acid, 3-oxo Tirucallic Acid
β؛ -Elemonic Acid هو triterpene معزول من Boswellia papyrifera. -
GC49769
β-Glucogallin
1-O-Galloyl-β-D-glucose
A plant metabolite and an aldose reductase 2 inhibitor -
GC64619
β-Ionone
β؛ -Ionone فعال في تحريض موت الخلايا المبرمج في الخلايا السرطانية المعدية SGC7901. نشاط مضاد للسرطان.
-
GC41502
β-Myrcene
NSC 406264
β ؛ -Myrcene (β-β ؛ -Myrcene) ، مركب عطري متطاير ، يمنع نشاط NF-B الناجم عن TNFα. -
GC72061
β-Phellandrene
β-Phellandrene يتم الحصول عليه من Carum البتروسيلينوم.
-
GC45604
β-Rubromycin
β ؛ -Rubromycin هو مثبط قوي وانتقائي لفيروس نقص المناعة البشرية -1 (HIV-1) بوليميرا الحمض النووي الريبي الموجه (النسخ العكسي).
-
GC52400
γ-Glu-Ala (trifluoroacetate salt)
γ-Glutamylalanine, γ-L-Glutamyl-L-alanine
A dipeptide -
GC48312
γ-Glu-Cys (ammonium salt)
γ-Glutamylcysteine
An intermediate in GSH synthesis -
GC45238
δ14-Triamcinolone acetonide
14,15-dehydro Triamcinolone acetonide, Triamcinolone acetonide Impurity B
δ14-Triamcinolone acetonide is a potential impurity found in commercial preparations of triamcinolone acetonide. -
GC40635
δ2-Avermectin B1a
δ2-Avermectin B1a is a degradation product formed by the reversible base-catalyzed isomerization of ivermectin B1a.
-
GC40307
δ2-cis-Hexadecenoic Acid
One of the first organisms in which quorum sensing was observed were Myxobacteria, a group of gram-negative bacteria, found mainly in soil and also common to marine and freshwater systems.
-
GC41393
ω-3 Arachidonic Acid methyl ester
ω-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and α-linoleate, are essential dietary nutrients required for normal growth and development.
-
GC41262
(±)-α-CMBHC
Vitamin E is a well known antioxidant that exists in eight natural forms: four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ).
-
GC41617
(±)-α-Tocopherol
all-rac-α-Tocopherol, DL-α-Tocopherol
(± ؛) - α ؛ -توكوفيرول هو فيتامين إي صناعي ، له تأثير مضاد للأكسدة. -
GC45713
(±)-α-Tocopherol Acetate
all-rac-α-Tocopherol Acetate, DL-α-Tocopherol Acetate, DL-Vitamin E acetate
(±؛) - α؛ -Tocopherol Acetate ((±؛) - أسيتات فيتامين E) ، هو شكل اصطناعي نشط عن طريق الفم من فيتامين E. -
GC46313
(±)-α-Tocopherol Acetate-d3
all-rac-α-Tocopherol Acetate-d3, DL-α-Tocopherol Acetate-d3, DL-Vitamin E Acetate-d3
A neuropeptide with diverse biological activities -
GC67191
(±)-α-Tocopherol nicotinate
(±؛) - α ؛ - توكوفيرول نيكوتينات ، فيتامين هـ - نيكوتينات ، هو أحد مضادات الأكسدة النشيطة التي تذوب في الدهون والتي تمنع بيروكسيد الدهون في أغشية الخلايا. (± ؛) - α ؛ - يتحلل توكوفيرول نيكوتينات في الدم إلى α ؛ - توكوفيرول ونياسين ويمكن استخدامهما في دراسات أمراض الأوعية الدموية ذات الصلة.
-
GC52010
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
αHYA, (±)-10-hydroxy-12(Z),15(Z)-ODE
An oxylipin gut microbiota metabolite -
GC52013
(±)-10-hydroxy-12(Z)-Octadecenoic Acid
10-hydroxy-cis-12-Octadecenoic Acid
An oxylipin and metabolite of linoleic acid -
GC52421
(±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5
10-hydroxy-cis-12-Octadecenoic Acid-d5
An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid -
GC45277
(±)-Camphene
DL-Camphene, NSC 4165
-
GC40112
(±)-Climbazole-d4
(±)-Climbazole-d4 is intended for use as an internal standard for the quantification of climbazole by GC- or LC-MS.
-
GC91298
(±)-Linalool-d3
معيار داخلي لتحديد كمية (±)-linalool
-
GC50708
(±)-ML 209
An RORγt antagonist
-
GC39271
(±)-Naringenin
SDihydrogenistein, NSC 11855, NSC 34875, Salipurol
(± ؛) - Naringenin هو فلافونويد طبيعي. -
GC90022
(±)-Norepinephrine-d6 (hydrochloride)
معيار داخلي لتحديد كمية النورأدرينالين
-
GC41212
(±)10(11)-EpDPA
(±)10,11-EDP, (±)10,11-EpDPE, (±)10,11-epoxy DPA, (±)10,11-epoxy Docosapentaenoic Acid
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. -
GC40466
(±)11(12)-EET
(±)11,12-EpETrE
(± ؛) 11 (12) -EET هو مثبط للالتهاب NLRP3. -
GC45922
(±)11(12)-EET-d11 methyl ester
(±)11,12-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC40467
(±)11-HETE
(±)11-Hydroxyeicosatetraenoic Acid
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. -
GC40802
(±)12(13)-DiHOME
Isoleukotoxin diol
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
-
GC46256
(±)12(13)-DiHOME-d4
Isoleukotoxin diold4
A neuropeptide with diverse biological activities -
GC41191
(±)13(14)-EpDPA
(±)13,14-EDP, (±)13,14-EpDPE, (±)13,14-epoxy DPA, (±)13,14-epoxy Docosapentaenoic Acid
(± ؛) 13 (14) -EpDPA (13،14-EpDPE) هو نتاج تفاعل السيتوكروم P-450 إيبوكسيجيناز مع حمض الدوكوساهيكسانويك (DHA). -
GC40355
(±)13-HpODE
13-Hydroperoxylinoleic acid; Linoleic acid 13-hydroperoxide
(± ؛) 13-HpODE (حمض 13-hydroperoxylinoleic) هو خليط راسيمي من hydroperoxides ، والذي ينتج عن طريق أكسدة حمض اللينوليك بواسطة lipoxygenase. -
GC41288
(±)17(18)-EpETE-Ethanolamide
17,18-EEQ-EA, (±)17,18-EEQ-Ethanolamide, (±)17(18)-EpETE-EA, 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. -
GC40362
(±)18-HEPE
(±)18-HEPE is produced by non-enzymatic oxidation of EPA.
-
GC41655
(±)19(20)-EDP Ethanolamide
19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). -
GC40270
(±)5(6)-DiHET
(±)5,6-DiHETrE
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC41203
(±)7(8)-EpDPA
(±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy DPA, (±)7,8-epoxy Docosapentaenoic Acid
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. -
GC40440
(±)8(9)-EET
(±)8,9EpETrE
(±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid. -
GC40838
(±)8(9)-EET methyl ester
(±)8,9EpETrE methyl ester
(±)8(9)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC46264
(±)8(9)-EET-d11
(±)8,9-EET-d11, (±)8,9-EpETrE-d11
A neuropeptide with diverse biological activities -
GC45921
(±)8(9)-EET-d11 methyl ester
(±)8,9-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC40801
(±)9(10)-DiHOME
Leukotoxin diol
(± ؛) 9 (10) -DiHOME هو رفاق سباق 9،10-DiHOME. -
GC40540
(±)9(10)-EpOME
Coronaric Acid, (±)9,10EODE, Leukotoxin
(±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. -
GC46000
(•)-Drimenol
NSC 169775
A sesquiterpene alcohol -
GC40809
(+)-β-Citronellol
(R)-Citronellol, (+)-Citronellol, (+)-(R)-Citronellol, (R)-(+)-β-Citronellol
(+) -β ؛ -Citronellol (D-Citronellol) هو مونوتربين كحولي موجود في زيت إبرة الراعي الأساسي. -
GC49268
(+)-δ-Cadinene
A sesquiterpene with antimicrobial and anticancer activities
-
GC41346
(+)-Cedrol
(+)-Cedrol is a sesquiterpene alcohol that has been used in Cannabis testing and has diverse biological activities.
-
GC45263
(+)-D-threo-PDMP (hydrochloride)
D-PDMP
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. -
GC31691
(+)-DHMEQ
(1R,2R,6R)-Dehydroxymethylepoxyquinomicin; (1R,2R,6R)-DHMEQ
(+) -DHMEQ هو منشط لعامل النسخ المضاد للأكسدة Nrf2. -
GC74247
(+)-Glaucarubinone
(+)-Glaucarubinone هو فعال منشط AP-1 بروتين مثبط -1 مع قيمة EC50 من 0.13 µM.
-
GC45266
(+)-Macrosphelide A
(+) -Macrosphelide A هو مضاد حيوي لماكرولايد.
-
GC40266
(+)-Praeruptorin A
(+) - Praeruptorin A هو أحد المكونات النشطة بيولوجيًا الرئيسية لـ Peucedanum praeruptorum (المعروف أيضًا باسم Bai-Hua Qian Hu).
-
GC18749
(+)-Rugulosin
NSC 160880, NSC 249990, Rugulosin A
(+) -Rugulosin هي مادة تلوين بلورية من Penicillium rugulosum Thom. -
GC63969
(+)-Schisandrin B
(+) - Schisandrin B هو مُصوّر لـ Schisandrin B
-
GC40264
(+)-Valencene
NSC 148969
(+)-Valencene is a sesquiterpene that has been found in C.
-
GC49502
(-)-β-Sesquiphellandrene
A sesquiterpene with antiviral and anticancer activities
-
GC32705
(-)-DHMEQ (Dehydroxymethylepoxyquinomicin)
Dehydroxymethylepoxyquinomicin
(-) - DHMEQ (Dehydroxymethylepoxyquinomicin) (Dehydroxymethylepoxyquinomicin) هو مادة NF-κ قوية وانتقائية ولا رجعة فيها ؛ مثبط B الذي يرتبط تساهميًا ببقايا السيستين. -
GC14049
(-)-Epigallocatechin gallate (EGCG)
EGCG
<بنزين فونول بأنشطة حيوية متعددة>
-
GC40218
(-)-Epigallocatechin Gallate-d3/d4
EGCG-d3/d4
(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS. -
GC45248
(-)-FINO2
(-) - FINO2 هو محفز قوي للتطعيم الحديدي. (-) - FINO2 يثبط نشاط GPX4. (-) - FINO2 هو عامل مؤكسد مستقر يؤكسد الحديد الحديدية ومستقر عند مستويات مختلفة من الأس الهيدروجيني. (-) - يتسبب FINO2 في انتشار بيروكسيد الدهون.
-
GC46245
(-)-G-Lactone
A bicyclic γ-lactone
-
GC38316
(-)-Limonene
(±)-Dipentene, DL-Limonene, NSC 844, NSC 21446
(-) - الليمونين ((S) - (-) - الليمونين) هو أحادي التربين موجود في العديد من زيوت إبرة الصنوبر وفي زيت التربنتين -
GC46247
(-)-Mycousnine
Mycousunin
A microbial metabolite with antibacterial and antifungal activities -
GC45251
(-)-Neplanocin A
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine.
-
GC90533
(-)-Pinoresinol
ليغنان بأنشطة حيوية متعددة
-
GC45272
(-)-Rasfonin
TT-1
(-) - Rasfonin هو مستقلب ثانوي فطري ويثبط بروتينات G الصغيرة Ras(-) - يحفز Rasfonin موت الخلايا المبرمج والنخر والالتهام الذاتي في خلايا ACHN (خط خلايا سرطان الكلى) -
GC40803
(25S)-δ7-Dafachronic Acid
UPF1404
During unfavorable environmental conditions, C. -
GC41697
(Ala1)-PAR4 (1-6) amide (mouse) (trifluoroacetate salt)
AY-NH2, AYPGKF-NH2, H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2, PAR4-AP, Proteinase-Activated Receptor 4 Activating Peptide
(Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively). -
GC52442
(D)-PPA 1 (trifluoroacetate salt)
DPPA-1, NYSKPTDRQYHF
An inhibitor of the PD-1-PD-L1 protein-protein interaction