Other Signal Transduction
Signal Transduction
Cellular responses are triggered by proteins, drugs, or pathogens binding to specific receptors. Receptor mediated signaling is a cascade of enzymatic reactions that amplifies the signal. The agonists and antagonists modulating receptor functionality are essential tools for research and medical practice. read more
أهداف لـ نبسب؛ Other Signal Transduction
منتجات لـ نبسب؛ Other Signal Transduction
- القط. رقم اسم المنتج بيانات
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GC49890
β-Glycerophosphate-d5 (sodium salt hydrate)
Glycerol 2-Phosphate-d5
An internal standard for the quantification of β-glycerophosphate -
GC13863
10Panx
10Panx
A peptide inhibitor of PANX1 -
GC49912
13C20,15N10-Cyclic di-GMP (sodium salt)
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid
An internal standard for the quantification of cyclic di-GMP - GC52141 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide
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GC52129
3-Amino-5-hydroxybenzoic Acid
AHBA
-
GC49494
4-Aminobenzylphosphonic Acid
4-ABPA, NSC 12117
An alkaline phosphatase inhibitor -
GP10121
Ac-Endothelin-1 (16-21), human
Ac-His-Leu-Asp-Ile-Ile-Trp-OH
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GP10059
Acetyl Angiotensinogen (1-14), porcine
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH
-
GP10076
Agouti-related Protein (AGRP) (25-82), human
H2N-Leu-Ala-Pro-Met-Glu-Gly-Ile-Arg-Arg-Pro-Asp-Gln-Ala-Leu-Leu-Pro-Glu-Leu-Pro-Gly-Leu-Gly-Leu-Arg-Ala-Pro-Leu-Lys-Lys-Thr-Thr-Ala-Glu-Gln-Ala-Glu-Glu-Asp-Leu-Leu-Gln-Glu-Ala-Gln-Ala-Leu-Ala-Glu-Val-Leu-Asp-Leu-Gln-Asp-Arg-Glu-Pro-Arg-OH
-
GC49110
AICA Ribonucleotide
AICA-Ribotide, AICA-Riboside-5'-phosphate, 5-Aminoimidazole-4-Carboxamide Ribonucelotide, NSC 283955, NSC 292227
An AMPK activator -
GC52361
AMARA Peptide (trifluoroacetate salt)
AMARAASAAALARRR-OH, H-Ala-Met-Ala-Arg-Ala-Ala-Ser-Ala-Ala-Ala-Leu-Ala-Arg-Arg-Arg-OH
A peptide substrate for AMPK -
GP10077
Angiotensin (1-7)
Asp-Arg-Val-Tyr-Ile-His-Pro
أنج-(1-7) (H - Asp - Arg - Val - Tyr - Ile - His - Pro - OH) هو قطعة ببتيدية ذاتية الإنتاج يمكن أن تُصَنَّع من Ang I أو Ang II عبر إستخدام إندو- أو كاربوكسي-بيبتيديز على الترتيب[1].
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GP10074
Angiotensin 1/2 (1-5)
H2N-Asp-Arg-Val-Tyr-Ile-OH
-
GP10067
Angiotensin 1/2 (1-6)
H2N-Asp-Arg-Val-Tyr-Ile-His-OH
-
GP10144
Angiotensin 1/2 (1-7) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide
-
GP10012
Angiotensin 1/2 (1-8) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide
Vasoconstrictor
- GP10025 Angiotensin 1/2 (1-9)
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GP10045
Angiotensin 1/2 (2-7)
H2N-Arg-Val-Tyr-Ile-His-Pro-OH
Vasoconstrictor
-
GP10079
Angiotensin 1/2 (5-7)
H2N-Ile-His-Pro-OH
-
GP10120
Angiotensin 1/2 + A (2 - 8)
H2N-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Vasoconstrictor - GP10087 Angiotensin I (human, mouse, rat)
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GP10023
Angiotensin II
محفز عند مستقبلات AT1 وAT2
- GP10110 Angiotensin III (human, mouse) An agonist at AT1 and AT2 receptors
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GP10137
ANP (1-11), rat
H2N-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH
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GP10061
Atrial Natriuretic Factor (1-29), chicken
H2N-Met-Met-Arg-Asp-Ser-Gly-Cys-Phe-Gly-Arg-Arg-Ile-Asp-Arg-Ile-Gly-Ser-Leu-Ser-Gly-Met-Gly-Cys-Asn-Gly-Ser-Arg-Lys-Asn-OH
Atrial Natriuretic Factor (1-29), chicken, (C130H223N51O41S5), a peptide with the sequence H2N-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH, MW= 3316.8. -
GC49403
Benzarone
L 2197, NSC 82134
Benzarone (Fragivix) هو مثبط فعال لنقل حمض اليوريك البشري 1 (hURAT1) ، مع IC 50 من 2.8 ميكرومتر في البويضة - GC49300 BIM-46187 (hydrochloride) An inhibitor of heterotrimeric G-protein signaling
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GC19508
BLU-782
Activin Receptor-like Kinase 2 Inhibitor 1, ALK2-IN-1, Fidrisertib
BLU-782 is an oral precision therapy specifically designed to selectively target mutant ALK2. - GP10071 BNP (1-32), human
- GC49079 C82 An Mtb CdnP inhibitor
-
GC49332
Calcineurin Substrate (trifluoroacetate salt)
H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH, H-DLDVPIPGRFDRRVSVAAE-OH
A synthetic peptide substrate - GC49433 Capsiate الكابسيات ، باعتباره نظير كبخاخات مستخرج من صنف غير لاذع من الفلفل الأحمر الحلو CH-19 ، هو ناهض فعال عن طريق الفم لـ TRPV1
- GC48992 CGP 77675 (hydrate) An inhibitor of Src family kinases
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GC49392
CHIR98024
CT 98024
CHIR98024 (المركب L) هو مثبط للجليكوجين سينثاز كيناز 3 (GSK3) مع EC50 من 0.2566 ميكرومتر. -
GC49334
Chroman 1 (hydrochloride hydrate)
(S)-Chroman 1
A ROCK2 inhibitor -
GC49556
Cl-Necrostatin-1
7-Cl-Nec-1, 7-Cl-Necrostatin-1, Nec-1f
A RIPK1 inhibitor -
GP10134
coagulation factor II (thrombin) B chain fragment [Homo sapiens]
H2N-Lys-Pro-Val-Ala-Phe-Ser-Asp-Tyr-Ile-His-Pro-Val-Cys-Leu-Pro-Asp-Arg-OH
-
GP10010
COG 133
Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu
-
GC49789
Dihydronarwedine
(–)-Dihydrogalanthaminone, (–)-Lycoraminone
An alkaloid and GSK3β inhibitor -
GP10022
Dynamin inhibitory peptide
Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro
-
GC13855
Eeyarestatin I
مثبط لتحلل الغشاء الخلوي المرتبط بالشبكة الإندوبلازمية ونقل البروتين.
-
GP10030
EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens]
Ac-Gln-Glu-Gln-Glu-Asp-Leu-Glu-Leu-Ala-Ile-Ala-Leu-Ser-Lys-Ser-Glu-Ile-Ser-Glu-Ala-OH
EGF receptor substrate eps15 (Eps15) has been identified as a 142-kDa substrate of the EGF receptor1. -
GP10108
EGF-R (661-681) T669 Peptide
H2N-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH
-
GC52002
Emavusertib
CA-4948
Emavusertib (CA-4948) هو مثبط قوي IRAK4 / FLT3 مع نشاط مضاد للورم - GP10065 Endomorphin-1
-
GP10117
Endostatin (84-114)-NH2 (JKC367)
H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
-
GP10062
Endothelin-1 (1-15), amide, human
H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-NH2
- GC52336 ENPP1 Inhibitor 43 An ENPP1 inhibitor
- GC52277 ENPP3 Inhibitor An ENPP3 inhibitor
- GC52362 ENPP3 Inhibitor 4g An ENPP1 and ENPP3 inhibitor
- GC52322 ENPP3 Inhibitor 4t An ENPP3 inhibitor
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GP10005
Epidermal growth factor receptor (994-1002) acetyl/amide
Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide
EGF-family receptor
-
GP10095
Epidermal Growth Factor Receptor Peptide (985-996)
H2N-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH
-
GP10132
erbB-2
H2N-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH
- GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase
-
GP10092
G protein coupled receptor [Homo sapiens]
H2N-Gln-Glu-Ser-His-Asn-Ser-Gly-Asn-Arg-Ser-Asp-Gly-Pro-Gly-Lys-Asn-Thr-Thr-Leu-His-Asn-Glu-Phe-Asp-Thr-OH
G protein coupled receptor [Homo sapiens], (C110H168N38O45), a peptide with the sequence H2N-QESHNSGNRSDGPGKNTTLHNEFDT-OH, MW= 2742.74. -
GP10107
Gap 26
Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg
-
GP10119
Gap 27
Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile
A connexin-mimetic peptide
-
GC25450
GATA4-NKX2-5-IN-1
3i-1000
GATA4-NKX2-5-IN-1 (3i-1000) is a small-molecule compound inhibiting GATA4 and NKX2-5 transcriptional synergy with IC50 of 3 uM
-
GP10122
Glucagon (19-29), human
H2N-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
-
GP10024
Growth Hormone (1-43), human
H2N-Phe-Pro-Thr-Ile-Pro-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala-Met-Leu-Arg-Ala-His-Arg-Leu-His-Gln-Leu-Ala-Phe-Asp-Thr-Tyr-Gln-Glu-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-OH
Human Growth Hormone (1-43) peptide - GC49284 GSK-A1 GSK-A1 عبارة عن مثبط انتقائي من النوع الثالث من فوسفاتيديلينوسيتول 4-كيناز PI4KA (PI4KIIIα) مع pIC50 من 8.5-9.8
-
GP10004
GTP binding protein 1 fragment [Multiple species]
H2N-Lys-Val-Ile-Thr-Phe-Ile-Asp-Leu-OH
Signal transducing molecules -
GP10115
GTP-Binding Protein Fragment, G alpha
H2N-Cys-Gly-Ala-Gly-Glu-Ser-Gly-Lys-Ser-Thr-Ile-Val-Lys-Gln-Met-Lys-OH
-
GP10041
Insulin like growth factor II fragment variant
H2N-Thr-Pro-Thr-Lys-Ser-Glu-Arg-OH
Insulin like growth factor II fragment variant has a sequence of Thr-Pro-Thr-Lys-Ser-Glu-Arg. -
GP10029
Interleukin II (60-70)
H2N-Leu-Thr-Phe-Lys-Phe-Tyr-Met-Pro-Lys-Lys-Ala-OH
Cytokine,regulating WBC
-
GC52328
KYL (trifluoroacetate salt)
KYL Peptide
An EphA4 inhibitor -
GC17779
Levetiracetam
UCBL 059
Levetiracetam ، وهو عامل مضاد للصرع ، يربط بروتين الحويصلة المشبكية SV2A -
GP10140
MAP kinase fragment [Multiple species]
H2N-Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu-OH
-
GP10066
Melanocyte stimulating hormone release inhibiting factor
Pro-Leu-Gly
-
GC49269
Myr-ZIP
Myristoylated-ZIP, Myristoylated Zeta-Pseudosubstrate Inhibitory Peptide, Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu, Myr-SIYRRGARRWRKL-OH, Ζeta Inhibitory Peptide
A PKMζ inhibitor -
GC49090
Nilvadipine-d4
(±)-Nilvadipine-d4
An internal standard for the quantification of nilvadipine -
GP10011
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell
Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys-OH
- GP10069 Parathyroid hormone (1-34) (human)
-
GC52151
PKCθ Inhibitor (hydrochloride)
Protein Kinase C θ Inhibitor
-
GC49265
PKI (14-22) amide (myristoylated) (trifluoroacetate salt)
Myr-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2, Myr-GRTGRRNAI-NH2, Myristoylated PKI-(14-22)-amide, PKI-(Myr-14-22)-amide
A PKA inhibitor -
GP10053
Prothrombin (474-477) [Mus musculus]
H2N-Tyr-Ile-His-Pro-OH
- GC49221 QLT0267 An ILK inhibitor
-
GP10042
Rhodopsin peptide
H2N-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH
- GC52115 S-99 An inhibitor of ASK1
-
GP10104
S6 Kinase Substrate Peptide 32
H2N-Lys-Glu-Ala-Lys-Glu-Lys-Arg-Gln-Glu-Gln-Ile-Ala-Lys-Arg-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-Ser-Thr-Ser-Lys-Ser-Gly-Gly-Ser-Gln-Lys-OH
Measures the activity of kinases that phosphorylate ribosomal protein S6. -
GC11058
Scrambled 10Panx
Scrambled 10Panx Phe-Ser-Val-Tyr-Trp-Ala-Gln-Ala-Asp-Arg
Panx-1 mimetic inhibitory peptide, blocks pannexin-1 gap junctions
-
GP10093
signal transducer and activator of transcription 5 (322-343) acetyl/amide
Ac-Asp-Ile-Ile-Ser-Ala-Leu-Val-Thr-Ser-Thr-Phe-Ile-Ile-Glu-Lys-Gln-Pro-Pro-Gln-Val-Leu-Lys-amide
signal transducer and activator of transcription 5 (322-343) acetylamide, (C115H193N27O33), a peptide with the sequence Ac-DIISALVTSTFIIEKQPPQVLK-amide, MW= 2481.92. -
GP10145
signal transducer and activator of transcription 6 fragment
H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH
-
GP10085
Thrombin Receptor Activator for Peptide 5 (TRAP-5)
H2N-Ser-Phe-Leu-Leu-Arg-OH
-
GC49692
Tofacitinib-d3 (citrate)
CP 690,550-d3
An internal standard for the quantification of tofacitinib -
GC49150
Tpl2 Kinase Inhibitor (hydrochloride)
c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor
A Tpl2 inhibitor -
GP10112
TRH Precursor Peptide
H2N-Lys-Arg-Gln-His-Pro-Gly-Lys-Arg-OH
Thyrotropin Releasing Hormone Precursor Peptide
-
GP10091
Vasonatrin Peptide (1-27)
H2N-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH
Vasonatrin Peptide (1-27), (C124H198N36O36S3), a peptide with the sequence H2N-GLSKGCFGLKLDRIGSMSGLGCNSFRY-OH, MW= 2865.4. -
GC52274
Y-33075 (hydrochloride)
RKI-983, SNJ-1656, Y-39983
An inhibitor of ROCK2 -
GP10017
[Ser25] Protein Kinase C (19-31)
H2N-Arg-Phe-Ala-Arg-Lys-Gly-Ser-Leu-Arg-Gln-Lys-Asn-Val-OH
PKC substrate
-
GP10096
β-Interleukin I (163-171), human
H2N-Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH
-
GP10080
β-Interleukin II (44-56)
H2N-Ile-Leu-Asn-Gly-Ile-Asn-Asn-Tyr-Lys-Asn-Pro-Lys-Leu-OH
-
GP10111
β-Pompilidotoxin
Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu