الصفحة الرئيسية>>Natural Products>>Zhebeirine

Zhebeirine

رقم الكتالوجGC61388

يتم عزل Zhebeirine (Puqiedinone) ، وهو قلويد الستيرويد ، من لمبات Fritillaria puqiensis

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Zhebeirine التركيب الكيميائي

Cas No.: 143120-47-2

الحجم السعر المخزون الكميّة
1mg
81٫00
متوفر
5mg
203٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.

Description of Zhebeirine

Zhebeirine (Puqiedinone), a steroidal alkaloid, is isolated from the bulbs of Fritillaria puqiensis. Zhebeirine exhibits antitussive and expectorant properties[1][2].

[1]. Lin G, et, al. Puqiedinone, a novel 5 alpha-cevanine alkaloid from the bulbs of Fritillaria puqiensis, an antitussive traditional Chinese medicine. J Nat Prod. 1995 Nov; 58(11):1662-7. [2]. Jiang Y, et, al. New steroidal alkaloids from the bulbs of Fritillaria puqiensis. Steroids. 2006 Sep; 71(9): 843-8.

Chemical Properties of Zhebeirine

Cas No. 143120-47-2 SDF
Canonical SMILES C[C@@]([C@]1([H])C[C@H]2O)(CC2)[C@]3([H])[C@](CC1=O)([H])[C@@](CC[C@@]4([H])[C@@]5([H])CN(C[C@@H]6C)[C@](CC6)([H])[C@@H]4C)([H])[C@@]5([H])C3
Formula C27H43NO2 M.Wt 413.64
الذوبان Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Zhebeirine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4176 mL 12.0878 mL 24.1756 mL
5 mM 483.5 μL 2.4176 mL 4.8351 mL
10 mM 241.8 μL 1.2088 mL 2.4176 mL
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In vivo Formulation Calculator (Clear solution) of Zhebeirine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Zhebeirine

Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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