Arecaidine |
| Catalog No.GC60596 |
Arecaidine, a pyridine alkaloid, is a potent GABA uptake inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 499-04-7
Sample solution is provided at 25 µL, 10mM.
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Arecaidine, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake[1][2].
[1]. D Lodge, et al. Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain Res. 1977 Nov 18;136(3):513-22. [2]. Valerie Voigt, et al. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). J Pharm Pharmacol. 2013 Apr;65(4):582-90.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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