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Arg-Gly-Asp (trifluoroacetate salt) (Synonyms: RGD)

Catalog No.GC52474

A synthetic peptide corresponding to an integrin cell adhesion sequence

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Arg-Gly-Asp (trifluoroacetate salt) Chemical Structure

Cas No.: 120103-89-1

Size Price Stock Qty
5 mg
$99.00
In stock
10 mg
$158.00
In stock
25 mg
$297.00
In stock
50 mg
$543.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1.1,2 It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.2,3

1.Ruoslahti, E.RGD and other recognition sequences for integrinsAnnu. Rev. Cell Dev. Biol.12697-715(1996) 2.Danhier, F., Le Breton, A., and PrÉat, V.RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosisMol. Pharm.9(11)2961-2973(2012) 3.Schottelius, M., Laufer, B., Kessler, H., et al.Ligands for mapping αvβ3-integrin expression in vivoAcc. Chem. Res.42(7)969-980(2009)

Chemical Properties

Cas No. 120103-89-1 SDF Download SDF
Synonyms RGD
Canonical SMILES N=C(N)NCCC[C@H](N)C(NCC(N[C@H](C(O)=O)CC(O)=O)=O)=O.OC(C(F)(F)F)=O
Formula C12H22N6O6 ? XCF3COOH M.Wt 346.3
Solubility PBS (pH 7.2): 10 mg/ml Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.8877 mL 14.4383 mL 28.8767 mL
5 mM 0.5775 mL 2.8877 mL 5.7753 mL
10 mM 0.2888 mL 1.4438 mL 2.8877 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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