ARRY-382 |
| Catalog No.GC60601 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1313407-95-2
Sample solution is provided at 25 µL, 10mM.
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ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers[1].
ARRY-382 (1 µM) dramatically decreases the number of nurse-like cells (NLCs) compared to untreated cells[1].
[1]. David K Edwards V, et al. Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget. 2018 May 15;9(37):24576-24589.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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