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Aurora B inhibitor 1 Catalog No.GC33379

Size Price Stock Qty
1mg
$754.00
In stock
5mg
$1,499.00
In stock
10mg
$2,684.00
In stock
20mg
$4,642.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Chemical Properties

Cas No. 937276-52-3 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES FC1(C2CC2)CN(C3=NC(O[C@@H]4CN(C(C5=C(C=CC(Cl)=C5)F)=O)CC4)=NC(NC6=NNC(C)=C6)=C3)C1
Formula C25H26ClF2N7O2 M.Wt 529.97
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.

Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively[1].

[1]. FRAYSSE, Damien, et al. AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS. WO2007059299A1.